Protein: EIF3G
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44)

Gene: EIF3G
Organism: Homo sapiens
Interactions: 225
UniProt ID: O75821

Gene Ontology (top 5):
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

275828

EIF3B
Eukaryotic translation initiation factor 3 subunit B

14

9

Small-scale

0.984

High

275863

EIF3I
Eukaryotic translation initiation factor 3 subunit I

10

5

Small-scale

0.973

High

275798

IF4B
Eukaryotic translation initiation factor 4B

2

17

Small-scale

0.789

High

275862

G3BP1
Ras GTPase-activating protein-binding protein 1

2

20

High-throughput

0.789

High

275870

EIF3A
Eukaryotic translation initiation factor 3 subunit A

9

8

Small-scale

0.755

High

275929

EIF3C
Eukaryotic translation initiation factor 3 subunit C

8

4

Small-scale

0.751

High

176896

EIF3H
Eukaryotic translation initiation factor 3 subunit H

8

12

Small-scale

0.751

High

124695

EIF3F
Eukaryotic translation initiation factor 3 subunit F

7

4

Small-scale

0.746

High

275831

EIF3E
Eukaryotic translation initiation factor 3 subunit E

6

2

Small-scale

0.733

High

275900

EIF3M
Eukaryotic translation initiation factor 3 subunit M

6

1

Small-scale

0.733

High

275958

EIF3L
Eukaryotic translation initiation factor 3 subunit L

5

2

High-throughput

0.718

High

176679

EIF3D
Eukaryotic translation initiation factor 3 subunit D

8

0

Small-scale

0.718

High

275948

EIF3K
Eukaryotic translation initiation factor 3 subunit K

4

1

Small-scale

0.696

High

275797

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.691

High

275851

RACK1
Small ribosomal subunit protein RACK1

1

7

High-throughput

0.691

High

275917

PSPC1
Paraspeckle component 1

1

17

High-throughput

0.691

High

275932

RBM42
RNA-binding protein 42

1

19

High-throughput

0.691

High

275956

G3BP2
Ras GTPase-activating protein-binding protein 2

1

20

High-throughput

0.691

High

275832

IF4A1
Eukaryotic initiation factor 4A-I

3

14

High-throughput

0.667

High

69223

MI4GD
MIF4G domain-containing protein

3

18

Small-scale

0.658

High

275882

PKN2
Serine/threonine-protein kinase N2

1

8

High-throughput

0.656

High

275840

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.656

High

275871

IF4A2
Eukaryotic initiation factor 4A-II

3

12

High-throughput

0.656

High

275757

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

16

Small-scale

0.647

High

226078

PRKN
E3 ubiquitin-protein ligase parkin

3

15

High-throughput

0.640

High

275855

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

3

19

Small-scale

0.640

High

275766

HERC2
E3 ubiquitin-protein ligase HERC2

3

9

Small-scale

0.633

High

275781

IF4E
Eukaryotic translation initiation factor 4E

2

5

High-throughput

0.628

High

275886

CERKL
Ceramide kinase-like protein

2

1

High-throughput

0.628

High

275891

PRC2B
Protein PRRC2B

2

16

High-throughput

0.628

High

275814

HD
Huntingtin

2

6

High-throughput

0.621

High

275794

CSK22
Casein kinase II subunit alpha'

1

10

High-throughput

0.618

High

275818

TISD
mRNA decay activator protein ZFP36L2

1

5

High-throughput

0.618

High

275852

CSK21
Casein kinase II subunit alpha

1

12

High-throughput

0.618

High

275853

SRSF3
Serine/arginine-rich splicing factor 3

1

19

Small-scale

0.618

High

275858

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

10

High-throughput

0.618

High

275873

RBM39
RNA-binding protein 39

1

16

High-throughput

0.618

High

275887

LARP7
La-related protein 7

1

18

High-throughput

0.618

High

275914

CSK23
Casein kinase II subunit alpha 3

1

12

High-throughput

0.618

High

275919

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

14

High-throughput

0.618

High

275939

RC3H2
Roquin-2

1

12

High-throughput

0.618

High

275954

FZR1
Fizzy-related protein homolog

1

8

High-throughput

0.618

High

275963

RBM8A
RNA-binding protein 8A

1

17

High-throughput

0.618

High

275827

IF5
Eukaryotic translation initiation factor 5

2

4

Small-scale

0.611

High

275931

PELO
Protein pelota homolog

1

3

Small-scale

0.598

High

275767

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

Small-scale

0.592

High

275787

EPB41
Protein 4.1

1

1

Small-scale

0.586

High

275857

EP300
Histone acetyltransferase p300

2

5

High-throughput

0.584

High

275758

EIF3J
Eukaryotic translation initiation factor 3 subunit J

2

0

Small-scale

0.576

High

275772

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.575

High

275892

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.575

High

275771

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

275796

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.571

High

275786

TAU
Microtubule-associated protein tau

2

12

High-throughput

0.552

High

78262

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

4

High-throughput

0.536

High

133796

DDX3X
ATP-dependent RNA helicase DDX3X

1

6

Small-scale

0.536

High

255009

ATG13
Autophagy-related protein 13

1

2

High-throughput

0.536

High

275759

SRP72
Signal recognition particle subunit SRP72

1

2

High-throughput

0.536

High

275779

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

2

High-throughput

0.536

High

275784

SRP19
Signal recognition particle 19 kDa protein

1

1

High-throughput

0.536

High

275790

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

12

High-throughput

0.536

High

275791

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.536

High

275795

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

4

High-throughput

0.536

High

275800

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

275805

BMI1
Polycomb complex protein BMI-1

1

12

High-throughput

0.536

High

275808

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.536

High

275812

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

9

High-throughput

0.536

High

275815

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.536

High

275816

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.536

High

275817

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

275819

PRC2A
Protein PRRC2A

1

15

High-throughput

0.536

High

275821

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

275824

MAP2
Methionine aminopeptidase 2

1

3

High-throughput

0.536

High

275825

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.536

High

275835

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.536

High

275836

RS7
Small ribosomal subunit protein eS7

1

2

High-throughput

0.536

High

275837

RS8
Small ribosomal subunit protein eS8

1

2

High-throughput

0.536

High

275838

RS16
Small ribosomal subunit protein uS9

1

6

High-throughput

0.536

High

275841

RS18
Small ribosomal subunit protein uS13

1

2

High-throughput

0.536

High

275842

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.536

High

275843

RS11
Small ribosomal subunit protein uS17

1

2

High-throughput

0.536

High

275846

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.536

High

275847

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.536

High

275868

CUL3
Cullin-3

1

20

High-throughput

0.536

High

275872

CAPR1
Caprin-1

1

5

High-throughput

0.536

High

275874

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

High-throughput

0.536

High

275875

CND2
Condensin complex subunit 2

1

2

High-throughput

0.536

High

275885

LSM12
Protein LSM12

1

4

High-throughput

0.536

High

275889

PDCD4
Programmed cell death protein 4

1

6

High-throughput

0.536

High

275897

DHX57
Putative ATP-dependent RNA helicase DHX57

1

13

High-throughput

0.536

High

275902

NUFP2
FMR1-interacting protein NUFIP2

1

3

High-throughput

0.536

High

275905

KTN1
Kinectin

1

6

High-throughput

0.536

High

275912

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

11

High-throughput

0.536

High

275927

DNJC2
DnaJ homolog subfamily C member 2

1

2

High-throughput

0.536

High

275930

ATX2
Ataxin-2

1

14

High-throughput

0.536

High

275937

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

18

Small-scale

0.536

High

275951

SRP68
Signal recognition particle subunit SRP68

1

2

High-throughput

0.536

High

275959

DRG1
Developmentally-regulated GTP-binding protein 1

1

3

High-throughput

0.536

High

275961

EMC9
ER membrane protein complex subunit 9

1

3

High-throughput

0.536

High

275962

PRC2C
Protein PRRC2C

1

14

High-throughput

0.536

High

275856

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.523

High

275910

FAM9B
Protein FAM9B

1

1

High-throughput

0.523

High

275898

PKHG7
Pleckstrin homology domain-containing family G member 7

2

6

High-throughput

0.521

High

239469

EIF1B
Eukaryotic translation initiation factor 1b

1

1

High-throughput

0.515

High

275964

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.515

High

261936

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.513

High

275807

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.513

High

275813

EIF2D
Eukaryotic translation initiation factor 2D

1

0

High-throughput

0.513

High

275848

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.513

High

275849

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

275850

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.513

High

275879

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.513

High

275908

ERI1
3'-5' exoribonuclease 1

1

0

High-throughput

0.513

High

275763

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

1

High-throughput

0.508

High

275809

SYUA
Alpha-synuclein

1

1

High-throughput

0.508

High

275826

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

2

High-throughput

0.508

High

275864

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.508

High

275884

SMN
Survival motor neuron protein

1

1

High-throughput

0.508

High

174494

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

275778

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

275765

KLF8
Krueppel-like factor 8

1

8

High-throughput

0.500

High

275934

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

6

High-throughput

0.500

High

275955

CAN11
Calpain-11

1

0

High-throughput

0.493

High

275785

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

275822

CTCF
Transcriptional repressor CTCF

1

3

High-throughput

0.489

High

275913

PDZD8
PDZ domain-containing protein 8

1

2

High-throughput

0.489

High

275940

ENY2
Transcription and mRNA export factor ENY2

1

3

High-throughput

0.489

High

275773

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

275770

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.481

High

275823

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

275869

TRI14
Tripartite motif-containing protein 14

1

6

High-throughput

0.481

High

275903

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

0

Small-scale

0.480

High

125052

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

8

High-throughput

0.479

High

203324

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

1

19

High-throughput

0.479

High

275760

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.479

High

275761

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

275762

HEXI1
Protein HEXIM1

1

4

High-throughput

0.479

High

275768

SNAI1
Zinc finger protein SNAI1

1

5

High-throughput

0.479

High

275769

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.479

High

275775

HG2A
HLA class II histocompatibility antigen gamma chain

1

1

High-throughput

0.479

High

275777

P53
Cellular tumor antigen p53

1

4

Small-scale

0.479

High

275782

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

275788

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.479

High

275793

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

275799

DDX6
Probable ATP-dependent RNA helicase DDX6

1

13

High-throughput

0.479

High

275802

PML
Protein PML

1

10

High-throughput

0.479

High

275803

1433S
14-3-3 protein sigma

1

8

Small-scale

0.479

High

275804

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

275810

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.479

High

275811

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

275833

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.479

High

275834

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

275839

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

275844

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

275845

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

275859

NFX1
Transcriptional repressor NF-X1

1

5

High-throughput

0.479

High

275860

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

4

High-throughput

0.479

High

275865

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

3

High-throughput

0.479

High

275866

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

1

3

High-throughput

0.479

High

275876

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

275877

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

275878

PCBP1
Poly(rC)-binding protein 1

1

20

Small-scale

0.479

High

275881

NF2L2
Nuclear factor erythroid 2-related factor 2

1

3

Small-scale

0.479

High

275888

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

10

High-throughput

0.479

High

275893

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

275894

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

275899

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

275904

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

275906

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

275907

ZCH18
Zinc finger CCCH domain-containing protein 18

1

11

High-throughput

0.479

High

275909

DDX60
Probable ATP-dependent RNA helicase DDX60

1

10

High-throughput

0.479

High

275911

CMTR1
Cap-specific mRNA

1

2

High-throughput

0.479

High

275916

BICD2
Protein bicaudal D homolog 2

1

7

High-throughput

0.479

High

275918

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

275921

CSN5
COP9 signalosome complex subunit 5

1

10

High-throughput

0.479

High

275924

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

275936

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

275938

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.479

High

275941

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

High-throughput

0.479

High

275942

ANLN
Anillin

1

6

High-throughput

0.479

High

275943

4ET
Eukaryotic translation initiation factor 4E transporter

1

2

High-throughput

0.479

High

275945

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

275949

DUX4
Double homeobox protein 4

1

9

High-throughput

0.479

High

275950

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

275952

UBQL2
Ubiquilin-2

1

4

High-throughput

0.479

High

275957

ANGE1
Protein angel homolog 1

1

4

High-throughput

0.479

High

275960

FND3A
Fibronectin type-III domain-containing protein 3A

1

6

High-throughput

0.479

High

275895

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

275764

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.458

High

275883

NREP
Neuronal regeneration-related protein

1

0

Small-scale

0.458

High

275933

KLF16
Krueppel-like factor 16

1

5

High-throughput

0.457

High

275953

KLF15
Krueppel-like factor 15

1

5

High-throughput

0.457

High

275789

TCTP
Translationally-controlled tumor protein

1

3

Small-scale

0.445

High

275867

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.445

High

275890

ODFP2
Outer dense fiber protein 2

1

2

High-throughput

0.445

High

275896

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

275926

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.445

High

275928

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.438

High

100321

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

243717

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.437

High

275774

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.437

High

275776

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.437

High

275780

ICAM1
Intercellular adhesion molecule 1

1

7

High-throughput

0.437

High

275792

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

275801

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

275806

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

275820

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.437

High

275829

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.437

High

275830

CD81
CD81 antigen

1

1

High-throughput

0.437

High

275854

RUNX1
Runt-related transcription factor 1

1

2

High-throughput

0.437

High

275861

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.437

High

275880

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.437

High

275901

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

275915

TIP
T-cell immunomodulatory protein

1

4

High-throughput

0.437

High

275920

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

275922

IGSF8
Immunoglobulin superfamily member 8

1

5

High-throughput

0.437

High

275925

CIC
Protein capicua homolog

1

13

High-throughput

0.437

High

275935

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.437

High

275947

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.426

High

275923

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.296

High

275944

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.282

High

234087

FADS1
Acyl-CoA

1

0

High-throughput

0.279

Low

275946

PALS2
Protein PALS2

1

0

High-throughput

0.251

Low

275783

5HT1A
5-hydroxytryptamine receptor 1A

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024