Protein: PARP8
Protein mono-ADP-ribosyltransferase PARP8 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 16) (ARTD16) (Poly [ADP-ribose] polymerase 8) (PARP-8)

Gene: PARP8
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q8N3A8

Gene Ontology (top 5):
GO:0003950 - NAD+ poly-ADP-ribosyltransferase activity
GO:0005635 - nuclear envelope
GO:0016779 - nucleotidyltransferase activity
GO:0019900 - kinase binding
GO:0030968 - endoplasmic reticulum unfolded protein response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

966604

1433G
14-3-3 protein gamma

3

5

High-throughput

0.604

High

1049550

1433F
14-3-3 protein eta

3

5

High-throughput

0.604

High

691237

1433T
14-3-3 protein theta

1

5

High-throughput

0.489

High

730048

1433B
14-3-3 protein beta/alpha

1

5

High-throughput

0.489

High

990489

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.489

High

1054485

EXOS9
Exosome complex component RRP45

1

1

High-throughput

0.489

High

1137640

EXOS7
Exosome complex component RRP42

1

1

High-throughput

0.489

High

895203

5HT6R
5-hydroxytryptamine receptor 6

1

0

High-throughput

0.282

High

253514

ANM3
Protein arginine N-methyltransferase 3

1

0

High-throughput

0.279

Low

370337

CYTA
Cystatin-A

1

0

High-throughput

0.279

Low

891242

GSK3A
Glycogen synthase kinase-3 alpha

1

0

High-throughput

0.279

Low

971773

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.279

Low

1010670

DCD
Dermcidin

1

0

High-throughput

0.279

Low

1324963

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.279

Low

1324964

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.279

Low

390665

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.249

Low

537508

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

650855

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.249

Low

1258505

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025