Protein: NOXO1
NADPH oxidase organizer 1 (NADPH oxidase regulatory protein) (Nox organizer 1) (Nox-organizing protein 1) (SH3 and PX domain-containing protein 5)

Gene: NOXO1
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q8NFA2

Gene Ontology (top 5):
GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0010310 - regulation of hydrogen peroxide metabolic process
GO:0016176 - superoxide-generating NADPH oxidase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1288875

NOXA1
NADPH oxidase activator 1

5

4

Small-scale

0.909

High

1338652

NOXO1
NADPH oxidase organizer 1

2

17

Small-scale

0.778

High

1017531

RHG08
Rho GTPase-activating protein 8

2

12

Small-scale

0.776

High

562804

CY24A
Cytochrome b-245 light chain

4

3

Small-scale

0.683

High

537545

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.536

High

861226

MAP1B
Microtubule-associated protein 1B

1

3

High-throughput

0.536

High

931006

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.536

High

1338653

PASK
PAS domain-containing serine/threonine-protein kinase

1

12

High-throughput

0.536

High

1338660

BAG5
BAG family molecular chaperone regulator 5

1

3

High-throughput

0.536

High

1338662

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

High-throughput

0.536

High

1338657

RGAP1
Rac GTPase-activating protein 1

1

9

Small-scale

0.514

High

1338663

NOX1
NADPH oxidase 1

1

1

Small-scale

0.501

High

1338654

ERBIN
Erbin

1

0

Small-scale

0.493

High

385992

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.489

High

962986

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.489

High

1226578

MAP1S
Microtubule-associated protein 1S

1

3

High-throughput

0.489

High

1220667

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

1338659

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

374077

RASN
GTPase NRas

1

11

Small-scale

0.445

High

452336

PDIA1
Protein disulfide-isomerase

1

3

Small-scale

0.445

High

528305

THIO
Thioredoxin

1

3

Small-scale

0.445

High

683871

MOES
Moesin

1

7

Small-scale

0.445

High

993250

ACTG
Actin, cytoplasmic 2

1

9

Small-scale

0.445

High

995153

CSK2B
Casein kinase II subunit beta

1

2

Small-scale

0.445

High

997873

CSK21
Casein kinase II subunit alpha

1

2

Small-scale

0.445

High

1100908

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

Small-scale

0.445

High

1338655

COR1B
Coronin-1B

1

8

Small-scale

0.445

High

361307

SODC
Superoxide dismutase [Cu-Zn]

1

0

Small-scale

0.426

High

405201

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

Small-scale

0.426

High

528773

MGST1
Microsomal glutathione S-transferase 1

1

0

Small-scale

0.426

High

625507

CSK22
Casein kinase II subunit alpha'

1

3

Small-scale

0.407

High

1337815

CSK23
Casein kinase II subunit alpha 3

1

2

Small-scale

0.407

High

1338658

TMX1
Thioredoxin-related transmembrane protein 1

1

3

Small-scale

0.407

High

1338661

COR1C
Coronin-1C

1

7

Small-scale

0.407

High

296724

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

1338656

PSMG3
Proteasome assembly chaperone 3

1

0

High-throughput

0.279

Low

647876

GPX3
Glutathione peroxidase 3

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025