Protein: CY24A
Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox)

Gene: CY24A, CYBA
Organism: Homo sapiens
Interactions: 64
UniProt ID: P13498

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001725 - stress fiber
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0003106 - negative regulation of glomerular filtration by angiotensin
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

416945

CY24B
NADPH oxidase 2

2

2

Small-scale

0.789

High

562774

NCF1
Neutrophil cytosol factor 1

5

3

Small-scale

0.720

High

562804

NOXO1
NADPH oxidase organizer 1

4

3

Small-scale

0.683

High

562817

NOX4
NADPH oxidase 4

1

2

Small-scale

0.618

High

562805

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

0

High-throughput

0.602

High

562806

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

2

1

Small-scale

0.549

High

562777

NCF2
Neutrophil cytosol factor 2

2

0

Small-scale

0.547

High

395407

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

165895

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.536

High

351869

S1PR4
Sphingosine 1-phosphate receptor 4

1

2

High-throughput

0.536

High

562776

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

1

Small-scale

0.536

High

562778

S1PR1
Sphingosine 1-phosphate receptor 1

1

2

High-throughput

0.536

High

562779

FPR2
N-formyl peptide receptor 2

1

1

High-throughput

0.536

High

562785

GPR12
G-protein coupled receptor 12

1

2

High-throughput

0.536

High

562787

TMEDA
Transmembrane emp24 domain-containing protein 10

1

1

High-throughput

0.536

High

562792

CCG7
Voltage-dependent calcium channel gamma-7 subunit

1

1

High-throughput

0.536

High

562795

TMED2
Transmembrane emp24 domain-containing protein 2

1

1

High-throughput

0.536

High

562809

RIFK
Riboflavin kinase

1

1

Small-scale

0.536

High

562818

C5AR2
C5a anaphylatoxin chemotactic receptor 2

1

1

High-throughput

0.536

High

562819

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

1

High-throughput

0.536

High

562820

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.536

High

165790

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

0

High-throughput

0.513

High

210696

KLK10
Kallikrein-10

1

0

High-throughput

0.513

High

212373

SPIT2
Kunitz-type protease inhibitor 2

1

0

High-throughput

0.513

High

260830

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

349368

TSN15
Tetraspanin-15

1

0

High-throughput

0.513

High

504830

H2AB1
Histone H2A-Bbd type 1

1

0

High-throughput

0.513

High

562775

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

562781

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

0

High-throughput

0.513

High

562786

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.513

High

562790

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.513

High

562797

T184A
Transmembrane protein 184A

1

0

High-throughput

0.513

High

562801

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

0

High-throughput

0.513

High

562802

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

562803

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

562813

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

0

High-throughput

0.513

High

562821

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

562822

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.513

High

562824

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.513

High

562794

NCF4
Neutrophil cytosol factor 4

1

2

Small-scale

0.501

High

562784

MAGA8
Melanoma-associated antigen 8

1

1

High-throughput

0.489

High

562788

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.460

High

562782

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

562791

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

562793

PAK1
Serine/threonine-protein kinase PAK 1

1

0

Small-scale

0.458

High

562812

DERL1
Derlin-1

1

0

Small-scale

0.458

High

562814

CARD9
Caspase recruitment domain-containing protein 9

1

0

Small-scale

0.458

High

371048

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.426

High

562789

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.426

High

562800

S22AG
Solute carrier family 22 member 16

1

0

High-throughput

0.426

High

562816

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

562807

APBP2
Amyloid protein-binding protein 2

1

0

Small-scale

0.305

High

562811

MDFI
MyoD family inhibitor

1

0

High-throughput

0.292

High

562798

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

562799

LYZL2
Lysozyme-like protein 2

1

0

High-throughput

0.279

Low

562823

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

562825

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.279

Low

562780

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.251

Low

562808

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.251

Low

562810

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.251

Low

562815

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.251

Low

293134

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

562783

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

562796

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025