Protein: P2RX7
P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)

Gene: P2RX7
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q99572

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000902 - cell morphogenesis
GO:0001530 - lipopolysaccharide binding
GO:0001614 - purinergic nucleotide receptor activity
GO:0001845 - phagolysosome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1146113

K1H1
Keratin, type I cuticular Ha1

3

1

High-throughput

0.616

High

572156

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

1330215

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

300472

KRT34
Keratin, type I cuticular Ha4

2

1

High-throughput

0.553

High

1405356

PKHF2
Pleckstrin homology domain-containing family F member 2

2

1

High-throughput

0.553

High

950637

KR108
Keratin-associated protein 10-8

1

1

High-throughput

0.523

High

168737

CSKP
Peripheral plasma membrane protein CASK

1

0

High-throughput

0.518

High

186438

TM9S1
Transmembrane 9 superfamily member 1

1

0

High-throughput

0.518

High

1153480

EFNB3
Ephrin-B3

1

0

High-throughput

0.518

High

609

NBPFJ
NBPF family member NBPF19

1

1

High-throughput

0.481

High

1277368

NT2NA
Notch homolog 2 N-terminal-like protein A

1

4

High-throughput

0.481

High

594087

NCK1
SH2/SH3 adapter protein NCK1

1

1

High-throughput

0.479

High

987888

GRB2
Growth factor receptor-bound protein 2

1

2

High-throughput

0.479

High

517091

NT2NC
Notch homolog 2 N-terminal-like protein C

1

4

High-throughput

0.470

High

272408

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

362356

ABL1
Tyrosine-protein kinase ABL1

1

0

High-throughput

0.458

High

845772

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

878546

PAXI
Paxillin

1

0

Small-scale

0.458

High

892431

CAMP
Cathelicidin antimicrobial peptide

1

0

Small-scale

0.458

High

640268

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.457

High

70436

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

269356

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

351590

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

0

High-throughput

0.316

High

106529

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025