Protein: WDR59
Maintenance of telomere capping protein 5 (SEH-associated protein 3)

Gene: WDR59, MTC5
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: Q03897

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005774 - vacuolar membrane
GO:0015031 - protein transport
GO:0034198 - cellular response to amino acid starvation
GO:0035591 - signaling adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

858400

SEH1
Nucleoporin SEH1

4

20

Small-scale

0.890

High

977806

SEC13
Protein transport protein SEC13

4

19

Small-scale

0.885

High

812611

IML1
Vacuolar membrane-associated protein IML1

3

11

Small-scale

0.834

High

977809

RTC1
Restriction of telomere capping protein 1

3

20

Small-scale

0.834

High

764761

NPR2
Nitrogen permease regulator 2

4

4

Small-scale

0.689

High

745400

SEA4
SEH-associated protein 4

3

6

Small-scale

0.646

High

753488

NPR3
Nitrogen permease regulator 3

3

1

Small-scale

0.646

High

450175

HSP73
Heat shock protein SSA3

3

20

High-throughput

0.593

High

556275

VATB
V-type proton ATPase subunit B

2

11

High-throughput

0.584

High

588214

HSP60
Heat shock protein 60, mitochondrial

2

20

High-throughput

0.533

High

969156

UBC7
Ubiquitin-conjugating enzyme E2 7

1

8

High-throughput

0.528

High

887665

ACT
Actin

1

9

High-throughput

0.514

High

478494

HSP77
Import motor subunit, mitochondrial

2

20

High-throughput

0.504

High

419952

SNF1
Carbon catabolite-derepressing protein kinase

1

7

High-throughput

0.500

High

424912

IF4E
Eukaryotic translation initiation factor 4E

1

4

High-throughput

0.489

High

526296

KIN2
Serine/threonine-protein kinase KIN2

1

8

High-throughput

0.489

High

532806

ACOX
Acyl-coenzyme A oxidase

1

3

High-throughput

0.489

High

602750

MCK1
Protein kinase MCK1

1

7

High-throughput

0.489

High

715850

MDJ1
DnaJ homolog 1, mitochondrial

1

14

High-throughput

0.489

High

752102

YHJ3
Uncharacterized protein YHR033W

1

4

High-throughput

0.489

High

761066

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.489

High

864176

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

High-throughput

0.489

High

977805

KU80
ATP-dependent DNA helicase II subunit 2

1

3

High-throughput

0.489

High

977808

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

977812

YO093
Uncharacterized protein YOR093C

1

6

High-throughput

0.470

High

334982

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

11

High-throughput

0.457

High

342771

ENO1
Enolase 1

1

5

High-throughput

0.457

High

366826

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.457

High

378392

LEU3
3-isopropylmalate dehydrogenase

1

11

High-throughput

0.457

High

381477

GAL1
Galactokinase

1

4

High-throughput

0.457

High

381715

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

2

High-throughput

0.457

High

397613

OTC
Ornithine carbamoyltransferase

1

6

High-throughput

0.457

High

427293

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

5

High-throughput

0.457

High

439562

GAL7
Galactose-1-phosphate uridylyltransferase

1

1

High-throughput

0.457

High

540153

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

5

High-throughput

0.457

High

554729

HSP26
Heat shock protein 26

1

4

High-throughput

0.457

High

605388

HSP74
Heat shock protein SSA4

1

20

High-throughput

0.457

High

687473

EF2
Elongation factor 2

1

10

High-throughput

0.457

High

703846

PRS6B
26S proteasome regulatory subunit 6B homolog

1

14

High-throughput

0.457

High

803410

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

9

High-throughput

0.457

High

811448

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.457

High

977813

HSP42
Heat shock protein 42

1

4

High-throughput

0.457

High

494856

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

566654

VATA
V-type proton ATPase catalytic subunit A

1

13

High-throughput

0.445

High

523436

SRS2
ATP-dependent DNA helicase SRS2

1

4

Small-scale

0.439

High

694221

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

3

High-throughput

0.437

High

753080

OSH3
Oxysterol-binding protein homolog 3

1

2

High-throughput

0.437

High

812111

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

970956

MLP1
Protein MLP1

1

20

High-throughput

0.437

High

977804

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

743663

HMT1
Protein arginine N-methyltransferase 1

1

9

High-throughput

0.417

High

342100

ATPB
ATP synthase subunit beta, mitochondrial

1

10

High-throughput

0.407

High

343680

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.407

High

423482

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

1

High-throughput

0.407

High

423903

ATPA
ATP synthase subunit alpha, mitochondrial

1

11

High-throughput

0.407

High

424692

PYR1
Multifunctional protein URA2

1

12

High-throughput

0.407

High

512574

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.407

High

562278

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

8

High-throughput

0.407

High

562429

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

8

High-throughput

0.407

High

604464

CLH
Clathrin heavy chain

1

9

High-throughput

0.407

High

619631

MPCP
Mitochondrial phosphate carrier protein

1

17

High-throughput

0.407

High

636730

CDC48
Cell division control protein 48

1

8

High-throughput

0.407

High

766186

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.407

High

769357

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.407

High

784352

COPB
Coatomer subunit beta

1

9

High-throughput

0.407

High

860591

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.407

High

867518

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

9

High-throughput

0.407

High

977811

CWC2
Pre-mRNA-splicing factor CWC2

1

2

High-throughput

0.407

High

977814

NOP58
Nucleolar protein 58

1

9

High-throughput

0.407

High

630435

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.279

Low

644821

RFA3
Replication factor A protein 3

1

0

High-throughput

0.279

Low

768371

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.279

Low

977810

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

0

High-throughput

0.279

Low

474405

YL016
Putative truncated guanine nucleotide exchange factor SDC25

1

0

High-throughput

0.261

Low

514650

FUS1
Nuclear fusion protein FUS1

1

0

High-throughput

0.261

Low

977807

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

653074

COQ8
Atypical kinase COQ8, mitochondrial

1

0

High-throughput

0.249

Low

758016

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

860943

SHY1
Cytochrome oxidase assembly protein SHY1

1

0

Small-scale

0.249

Low

977803

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

732177

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.232

Low

777138

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024