Protein: IL21
Interleukin-21 (IL-21) (Za11)

Gene: IL21
Organism: Homo sapiens
Interactions: 12
UniProt ID: Q9HBE4

Gene Ontology (top 5):
GO:0001779 - natural killer cell differentiation
GO:0001819 - positive regulation of cytokine production
GO:0002314 - germinal center B cell differentiation
GO:0002639 - positive regulation of immunoglobulin production
GO:0002729 - positive regulation of natural killer cell cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

728687

IL2RG
Cytokine receptor common subunit gamma

1

0

Small-scale

0.654

High

445263

S10A6
Protein S100-A6

1

1

Small-scale

0.501

High

682617

S100P
Protein S100-P

1

1

Small-scale

0.501

High

827930

STAT3
Signal transducer and activator of transcription 3

1

3

Small-scale

0.479

High

838181

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

3

Small-scale

0.479

High

913166

STAT2
Signal transducer and activator of transcription 2

1

3

Small-scale

0.479

High

1132034

STAT4
Signal transducer and activator of transcription 4

1

3

Small-scale

0.437

High

1086113

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.316

High

358904

AL1A1
Aldehyde dehydrogenase 1A1

1

0

High-throughput

0.269

Low

1349768

FBX25
F-box only protein 25

1

0

Small-scale

0.261

Low

605094

JUND
Transcription factor JunD

1

0

Small-scale

0.249

Low

1438142

PARP2
Poly [ADP-ribose] polymerase 2

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025