Protein: METK
S-adenosylmethionine synthase (AdoMet synthase) (EC 2.5.1.6) (MAT) (Methionine adenosyltransferase)

Gene: METK
Organism: Escherichia coli K-12
Interactions: 46
UniProt ID: P0A817

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004478 - methionine adenosyltransferase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006556 - S-adenosylmethionine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

462778

METK
S-adenosylmethionine synthase

2

15

Small-scale

0.768

High

457546

CH60
Chaperonin GroEL

2

0

Small-scale

0.592

High

458342

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

2

1

High-throughput

0.588

High

458377

HSLU
ATP-dependent protease ATPase subunit HslU

2

1

High-throughput

0.588

High

462780

MREB
Cell shape-determining protein MreB

2

6

High-throughput

0.588

High

340909

DPO1
DNA polymerase I

2

0

High-throughput

0.563

High

458681

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

2

0

High-throughput

0.563

High

460329

RECA
Protein RecA

2

0

High-throughput

0.563

High

462781

PSTB
Phosphate import ATP-binding protein PstB

2

0

High-throughput

0.563

High

462784

GYRA
DNA gyrase subunit A

2

0

High-throughput

0.563

High

462785

GYRB
DNA gyrase subunit B

2

0

High-throughput

0.563

High

462786

SRP54
Signal recognition particle protein

2

0

High-throughput

0.563

High

462787

IBPA
Small heat shock protein IbpA

2

0

High-throughput

0.563

High

462790

SECA
Protein translocase subunit SecA

2

0

High-throughput

0.563

High

459636

KPRS
Ribose-phosphate pyrophosphokinase

1

1

High-throughput

0.536

High

462791

PHNN
Ribose 1,5-bisphosphate phosphokinase PhnN

1

0

High-throughput

0.513

High

462792

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

462800

SPEB
Agmatinase

1

0

High-throughput

0.513

High

442667

DNAJ
Chaperone protein DnaJ

1

4

High-throughput

0.484

High

459059

DNAK
Chaperone protein DnaK

1

2

High-throughput

0.484

High

462788

EFTU1
Elongation factor Tu 1

1

1

High-throughput

0.484

High

343881

SYGA
Glycine--tRNA ligase alpha subunit

1

0

High-throughput

0.464

High

393731

PNP
Polyribonucleotide nucleotidyltransferase

1

0

High-throughput

0.464

High

421092

MALT
HTH-type transcriptional regulator MalT

1

0

High-throughput

0.464

High

449033

GRPE
Protein GrpE

1

0

High-throughput

0.464

High

458293

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.464

High

459586

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

462797

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.464

High

409408

TSAD
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

458524

HSCB
Co-chaperone protein HscB

1

0

High-throughput

0.458

High

462803

LOLD
Lipoprotein-releasing system ATP-binding protein LolD

1

0

High-throughput

0.458

High

462804

DXS
1-deoxy-D-xylulose-5-phosphate synthase

1

0

High-throughput

0.458

High

462799

FLII
Flagellum-specific ATP synthase

1

1

High-throughput

0.457

High

462789

EFTU2
Elongation factor Tu 2

1

1

High-throughput

0.445

High

462796

CBPA
Curved DNA-binding protein

1

1

High-throughput

0.442

High

427788

CHEA
Chemotaxis protein CheA

1

0

High-throughput

0.438

High

462779

TIG
Trigger factor

1

0

High-throughput

0.438

High

462783

FLIT
Flagellar protein FliT

1

0

High-throughput

0.438

High

462802

FLGF
Flagellar basal-body rod protein FlgF

1

1

High-throughput

0.417

High

462782

FDNH
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit

2

0

High-throughput

0.318

High

462793

YBFC
Uncharacterized protein YbfC

1

0

High-throughput

0.279

Low

462798

DEGQ
Periplasmic pH-dependent serine endoprotease DegQ

1

0

High-throughput

0.279

Low

462795

NUOCD
NADH-quinone oxidoreductase subunit C/D

1

0

High-throughput

0.249

Low

462801

YODC
Uncharacterized protein YodC

1

0

High-throughput

0.249

Low

462794

FLIR
Flagellar biosynthetic protein FliR

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024