Protein: OYE2
NADPH dehydrogenase 2 (EC 1.6.99.1) (Old yellow enzyme 2)

Gene: OYE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: Q03558

Gene Ontology (top 5):
GO:0003959 - NADPH dehydrogenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

836170

OYE3
NADPH dehydrogenase 3

2

1

High-throughput

0.767

High

850178

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

527552

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

546084

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

819652

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

671064

SIS1
Protein SIS1

2

0

High-throughput

0.547

High

449175

CALM
Calmodulin

1

0

Small-scale

0.537

High

656602

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.536

High

709452

HRR25
Casein kinase I homolog HRR25

1

1

High-throughput

0.536

High

1027270

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

High-throughput

0.536

High

510779

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.513

High

802897

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.513

High

1043353

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.513

High

1043356

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.513

High

1043357

BUD20
Bud site selection protein 20

1

0

High-throughput

0.513

High

1043366

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

0

High-throughput

0.513

High

1043367

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.513

High

815555

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

High-throughput

0.501

High

809093

DUN1
DNA damage response protein kinase DUN1

1

1

High-throughput

0.500

High

703896

RAD14
DNA repair protein RAD14

1

0

High-throughput

0.493

High

1043371

GST2
Glutathione S-transferase 2

1

0

High-throughput

0.493

High

750295

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.480

High

459154

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.479

High

576990

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.479

High

1043372

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.479

High

367805

ENO1
Enolase 1

1

1

High-throughput

0.479

High

368043

ENO2
Enolase 2

1

1

High-throughput

0.479

High

393246

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

439413

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

579976

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

865730

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

1042211

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

1043355

ARO10
Transaminated amino acid decarboxylase

1

1

High-throughput

0.479

High

623937

MYO2
Myosin-2

1

0

Small-scale

0.460

High

1043364

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

1043368

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

359060

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.458

High

365688

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

368481

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

368739

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

416475

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

555145

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

646518

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

697336

COQ8
Atypical kinase COQ8, mitochondrial

1

0

High-throughput

0.458

High

708030

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

721275

PSB5
Proteasome subunit beta type-5

1

0

High-throughput

0.458

High

745860

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

752673

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

797042

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

803670

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

806808

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

807059

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

918671

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

919079

YG2W
Uncharacterized protein YGR111W

1

0

High-throughput

0.458

High

925379

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

1040546

ESP1
Separin

1

0

High-throughput

0.458

High

1043350

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

1043354

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

1043360

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

1043361

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

1043362

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

1043365

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

524988

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

742287

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

948639

ACT
Actin

1

0

Small-scale

0.438

High

597259

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

804416

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

1043369

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

1035058

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

782429

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

924922

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.279

Low

1043351

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

1043352

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

1043363

YP150
Putative serine/threonine-protein kinase YPL150W

1

0

High-throughput

0.279

Low

1043358

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

0

High-throughput

0.269

Low

737032

CDC3
Cell division control protein 3

1

0

High-throughput

0.261

Low

748194

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

798019

YB69
Uncharacterized protein YBR219C

1

0

High-throughput

0.249

Low

798697

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

1043359

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

1043370

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

1043373

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025