Protein: HIS1
ATP phosphoribosyltransferase (ATP-PRT) (ATP-PRTase) (EC 2.4.2.17)

Gene: HIS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 33
UniProt ID: P00498

Gene Ontology (top 5):
GO:0000105 - L-histidine biosynthetic process
GO:0000287 - magnesium ion binding
GO:0003879 - ATP phosphoribosyltransferase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

361952

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

361959

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

361950

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

361953

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

361954

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

361961

DDR48
Stress protein DDR48

1

0

High-throughput

0.458

High

361969

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

361972

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

361975

RTS2
Zinc finger protein RTS2

1

0

High-throughput

0.458

High

361977

COFI
Cofilin

1

0

High-throughput

0.458

High

361981

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

361982

DPH3
Diphthamide biosynthesis protein 3

1

0

High-throughput

0.458

High

361955

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

361956

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

361957

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

361974

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

361966

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

361967

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

361960

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

361978

POB3
FACT complex subunit POB3

2

0

High-throughput

0.305

High

361951

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.249

Low

361958

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

361962

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

361963

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

361964

SGF29
SAGA complex subunit SGF29

1

0

Small-scale

0.249

Low

361965

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

361968

SPT16
FACT complex subunit SPT16

1

0

Small-scale

0.249

Low

361971

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

361973

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

361976

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

361979

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

361980

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

361970

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025