Protein: TCTP
Translationally-controlled tumor protein homolog (TCTP) (Microtubule and mitochondria-interacting protein 1) (Translation machinery-associated protein 19)

Gene: TCTP, TMA19
Organism: Saccharomyces cerevisiae S288C
Interactions: 93
UniProt ID: P35691

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

775958

TCTP
Translationally-controlled tumor protein homolog

1

2

High-throughput

0.618

High

670561

SIS1
Protein SIS1

2

3

High-throughput

0.601

High

713609

EF1G1
Elongation factor 1-gamma 1

2

3

High-throughput

0.601

High

775961

EF1G2
Elongation factor 1-gamma 2

2

3

High-throughput

0.601

High

416415

HXKA
Hexokinase-1

2

2

High-throughput

0.594

High

775976

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

2

High-throughput

0.584

High

523565

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

775970

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.552

High

746343

RAD54
DNA repair and recombination protein RAD54

1

3

High-throughput

0.536

High

775979

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

775982

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

709352

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

737301

CDC12
Cell division control protein 12

1

0

High-throughput

0.513

High

775995

CUE5
Ubiquitin-binding protein CUE5

1

0

Small-scale

0.513

High

602401

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.501

High

607748

HXKG
Glucokinase-1

1

2

High-throughput

0.500

High

736786

AROG
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited

1

0

High-throughput

0.493

High

775993

SDO1
Ribosome maturation protein SDO1

1

0

High-throughput

0.493

High

750583

UBC6
Ubiquitin-conjugating enzyme E2 6

1

5

High-throughput

0.489

High

358997

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.479

High

365011

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.479

High

365600

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.479

High

367732

ENO1
Enolase 1

1

2

High-throughput

0.479

High

367941

ENO2
Enolase 2

1

2

High-throughput

0.479

High

368641

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

392534

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

401960

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.479

High

416538

HXKB
Hexokinase-2

1

2

High-throughput

0.479

High

504145

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

579169

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

655566

TKT1
Transketolase 1

1

1

High-throughput

0.479

High

674536

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

679552

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

737366

EF1B
Elongation factor 1-beta

1

4

High-throughput

0.479

High

740648

CBS
Cystathionine beta-synthase

1

1

High-throughput

0.479

High

775962

NDK
Nucleoside diphosphate kinase

1

1

High-throughput

0.479

High

775963

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

775965

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

775975

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.479

High

775986

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

775988

HMO1
High mobility group protein 1

1

1

High-throughput

0.479

High

775980

RHO5
GTP-binding protein RHO5

1

0

Small-scale

0.460

High

361969

HIS1
ATP phosphoribosyltransferase

1

0

High-throughput

0.458

High

368431

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

383622

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

439306

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

454096

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.458

High

454980

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

514563

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

555054

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

572554

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

575922

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

578226

TAL1
Transaldolase

1

0

High-throughput

0.458

High

734927

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747282

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

750619

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

775959

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

775960

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

775964

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

775966

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

775967

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

775969

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

775971

MMF1
Protein MMF1, mitochondrial

1

0

High-throughput

0.458

High

775972

MLP2
Protein MLP2

1

0

High-throughput

0.458

High

775974

ELP2
Elongator complex protein 2

1

0

High-throughput

0.458

High

775977

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

775978

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

775981

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

775983

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

775985

COFI
Cofilin

1

0

High-throughput

0.458

High

775994

ZEO1
Protein ZEO1

1

0

High-throughput

0.458

High

775996

SGO1
Shugoshin

1

0

High-throughput

0.458

High

526364

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

544407

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

752100

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

775990

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

6

High-throughput

0.445

High

775973

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.439

High

775984

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.439

High

682234

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

775987

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

776000

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

684065

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.279

Low

775968

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.279

Low

775989

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

594304

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.249

Low

605104

TPM1
Tropomyosin-1

1

0

High-throughput

0.249

Low

706736

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

775991

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

775992

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

775997

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

775998

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.249

Low

775999

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025