Protein: MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)] (EC 1.5.1.15)

Gene: MTD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 25
UniProt ID: Q02046

Gene Ontology (top 5):
GO:0004487 - methylenetetrahydrofolate dehydrogenase (NAD+) activity
GO:0004488 - methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006164 - purine nucleotide biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1034638

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

2

6

Small-scale

0.786

High

393194

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.571

High

1034640

ARO80
Transcriptional activator ARO80

1

0

High-throughput

0.518

High

364700

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.501

High

599391

FUS3
Mitogen-activated protein kinase FUS3

1

2

High-throughput

0.501

High

645970

DBF2
Cell cycle protein kinase DBF2

1

1

High-throughput

0.501

High

709448

HRR25
Casein kinase I homolog HRR25

1

1

High-throughput

0.501

High

847820

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.486

High

1034643

SKS1
Serine/threonine-protein kinase SKS1

1

0

High-throughput

0.480

High

579918

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

707939

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

836320

BNI1
Protein BNI1

1

1

High-throughput

0.479

High

1034641

SUB2
ATP-dependent RNA helicase SUB2

1

3

High-throughput

0.479

High

668289

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

744539

DRI1
Putative RNA-binding protein involved in heterochromatin assembly

1

0

High-throughput

0.458

High

1034639

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

545945

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

806343

KOG1
Target of rapamycin complex 1 subunit KOG1

1

2

High-throughput

0.439

High

865940

YJ66
Uncharacterized oxidoreductase YJR096W

1

0

High-throughput

0.438

High

518371

IF4A
ATP-dependent RNA helicase eIF4A

1

3

High-throughput

0.437

High

795156

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

919245

YG3A
Uncharacterized protein YGR130C

1

3

High-throughput

0.417

High

704902

KIP2
Kinesin-like protein KIP2

1

0

High-throughput

0.249

Low

1034642

SNA4
Protein SNA4

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025