Protein: PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Phosphatase two C protein 5) (Protein phosphatase 2C homolog 5) (PP2C-5) (Protein phosphatase of PDH protein 1) (Pyruvate dehydrogenase complex phosphatase 1) (PDC phosphatase 1)

Gene: PDP1, PTC5
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: Q12511

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004741 - [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1027307

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

11

High-throughput

0.621

High

1085021

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

2

High-throughput

0.618

High

452542

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

2

0

High-throughput

0.585

High

393581

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.555

High

528112

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.536

High

1046971

POB3
FACT complex subunit POB3

2

1

High-throughput

0.533

High

825789

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.513

High

670367

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.489

High

421004

PMA1
Plasma membrane ATPase 1

1

2

High-throughput

0.479

High

510932

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.479

High

732896

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

745147

YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1

1

3

High-throughput

0.479

High

746597

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

1

High-throughput

0.479

High

779391

CENPA
Histone H3-like centromeric protein CSE4

1

2

High-throughput

0.479

High

780520

MCR1
NADH-cytochrome b5 reductase 2

1

1

High-throughput

0.479

High

792755

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

1

High-throughput

0.479

High

795675

MOH1
Protein yippee-like MOH1

1

1

High-throughput

0.479

High

804836

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

3

High-throughput

0.479

High

807044

CYC2
Cytochrome c mitochondrial import factor CYC2

1

1

High-throughput

0.479

High

820813

CCS1
Superoxide dismutase 1 copper chaperone

1

2

High-throughput

0.479

High

821008

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

1

High-throughput

0.479

High

829861

PHB1
Prohibitin-1

1

1

High-throughput

0.479

High

893063

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

1059545

NDH2
External NADH-ubiquinone oxidoreductase 2, mitochondrial

1

1

High-throughput

0.479

High

1061491

FMP25
Protein FMP25, mitochondrial

1

1

High-throughput

0.479

High

360687

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.458

High

383020

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

450468

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

470215

NUC1
Mitochondrial nuclease

1

0

High-throughput

0.458

High

623758

COX11
Cytochrome c oxidase assembly protein COX11, mitochondrial

1

0

High-throughput

0.458

High

661834

TOM40
Mitochondrial import receptor subunit TOM40

1

0

High-throughput

0.458

High

677091

MGR1
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1

1

0

High-throughput

0.458

High

713521

TRXB1
Thioredoxin reductase 1

1

0

High-throughput

0.458

High

733643

MGM1
Dynamin-like GTPase MGM1, mitochondrial

1

0

High-throughput

0.458

High

763706

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

0

High-throughput

0.458

High

782608

OMA1
Mitochondrial metalloendopeptidase OMA1

1

0

High-throughput

0.458

High

792765

SCO2
Protein SCO2, mitochondrial

1

0

High-throughput

0.458

High

809012

PSD1
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial

1

0

High-throughput

0.458

High

814422

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.458

High

816827

FMP52
Protein FMP52, mitochondrial

1

0

High-throughput

0.458

High

823460

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.458

High

864460

TIM54
Mitochondrial import inner membrane translocase subunit TIM54

1

0

High-throughput

0.458

High

922864

RCF2
Respiratory supercomplex factor 2, mitochondrial

1

0

High-throughput

0.458

High

1017962

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

1

0

High-throughput

0.458

High

1038565

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.458

High

1039597

FMP30
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial

1

0

High-throughput

0.458

High

1056385

OMS1
Methyltransferase OMS1, mitochondrial

1

0

High-throughput

0.458

High

1084387

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

1084530

MDM32
Mitochondrial distribution and morphology protein 32

1

0

High-throughput

0.458

High

580303

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.445

High

513433

RL23B
Large ribosomal subunit protein uL14B

1

1

High-throughput

0.437

High

739835

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

904474

GCH1
GTP cyclohydrolase 1

1

1

High-throughput

0.437

High

1046469

HNT1
Adenosine 5'-monophosphoramidase HNT1

1

1

High-throughput

0.437

High

525663

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.407

High

546884

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

742757

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.407

High

824597

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.407

High

826965

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

801801

KPR3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.279

Low

823416

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.279

Low

1085022

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.279

Low

788436

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.269

Low

531940

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

603578

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.249

Low

644651

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.249

Low

802461

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

805659

LSM12
Protein LSM12

1

0

High-throughput

0.249

Low

807183

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.249

Low

807800

CSK2C
Casein kinase II subunit beta'

1

0

High-throughput

0.249

Low

820508

PIG2
GSY2-interacting protein PIG2

1

0

High-throughput

0.249

Low

820894

SIP5
Protein SIP5

1

0

High-throughput

0.249

Low

861050

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.249

Low

919746

SCW4
Probable family 17 glucosidase SCW4

1

0

High-throughput

0.249

Low

932194

ERG5
C-22 sterol desaturase ERG5

1

0

High-throughput

0.249

Low

1054025

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1055684

CDD
Cytidine deaminase

1

0

High-throughput

0.249

Low

1059592

KAR
NADPH-dependent alpha-keto amide reductase

1

0

High-throughput

0.249

Low

671282

SIS1
Protein SIS1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025