Protein: PYRF
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase) (Uridine 5'-monophosphate synthase) (UMP synthase)

Gene: PYRF, URA3
Organism: Saccharomyces cerevisiae S288C
Interactions: 36
UniProt ID: P03962

Gene Ontology (top 5):
GO:0004590 - orotidine-5'-phosphate decarboxylase activity
GO:0005829 - cytosol
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006222 - UMP biosynthetic process
GO:0044205 - 'de novo' UMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

399289

PYRF
Orotidine 5'-phosphate decarboxylase

2

3

Small-scale

0.767

High

399301

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.513

High

399317

YMW4
Uncharacterized protein YMR074C

1

0

High-throughput

0.493

High

368530

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.479

High

399290

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

399297

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

399300

BPH1
Beige protein homolog 1

1

0

High-throughput

0.458

High

399307

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

391943

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

399292

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

399293

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

399294

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

399296

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

399305

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

399306

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

399313

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

399291

PBS2
MAP kinase kinase PBS2

1

2

High-throughput

0.437

High

399298

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

399302

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

399308

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

399295

SEC63
Protein translocation protein SEC63

1

0

Small-scale

0.251

Low

399299

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

399303

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.249

Low

399304

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.249

Low

399310

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.249

Low

399318

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

399319

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

399321

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.249

Low

399309

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

399311

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low

399312

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

399314

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

399315

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

399316

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

399320

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025