Protein: PSD4
PH and SEC7 domain-containing protein 4 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B) (Exchange factor for ARF6 B) (Pleckstrin homology and SEC7 domain-containing protein 4) (Telomeric of interleukin-1 cluster protein)

Gene: PSD4
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q8NDX1

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005543 - phospholipid binding
GO:0016020 - membrane
GO:0032012 - regulation of ARF protein signal transduction
GO:0032587 - ruffle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

975133

ARF6
ADP-ribosylation factor 6

1

14

Small-scale

0.647

High

1211060

ARH
Low density lipoprotein receptor adapter protein 1

4

4

High-throughput

0.643

High

1326491

ARL14
ADP-ribosylation factor-like protein 14

1

16

Small-scale

0.579

High

1336906

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

Small-scale

0.537

High

540053

BCR
Breakpoint cluster region protein

1

7

High-throughput

0.536

High

966634

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

971795

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.536

High

1139019

SNX17
Sorting nexin-17

1

1

High-throughput

0.536

High

593683

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

990513

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.489

High

1271649

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

2

High-throughput

0.489

High

1336907

GULP1
PTB domain-containing engulfment adapter protein 1

1

6

High-throughput

0.489

High

1122418

GIT2
ARF GTPase-activating protein GIT2

1

9

High-throughput

0.479

High

1336909

GIT1
ARF GTPase-activating protein GIT1

1

7

High-throughput

0.479

High

374778

RASH
GTPase HRas

1

11

High-throughput

0.437

High

896693

ASCL1
Achaete-scute homolog 1

1

4

High-throughput

0.437

High

1227081

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.437

High

1336908

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

416759

TYSY
Thymidylate synthase

1

0

High-throughput

0.279

Low

1257791

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.279

Low

1315337

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.279

Low

1023837

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025