Protein: THNS1
Threonine synthase-like 1 (TSH1)

Gene: THNS1, THNSL1
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q8IYQ7

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315360

UTP11
Probable U3 small nucleolar RNA-associated protein 11

3

0

High-throughput

0.638

High

1315343

CC74B
Coiled-coil domain-containing protein 74B

3

1

High-throughput

0.609

High

946503

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1292070

SPA24
Spermatogenesis-associated protein 24

2

0

High-throughput

0.602

High

1315348

MGME1
Mitochondrial genome maintenance exonuclease 1

2

0

High-throughput

0.602

High

279826

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.584

High

1123344

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.559

High

1162416

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

946429

MTPN
Myotrophin

1

1

High-throughput

0.536

High

1287718

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

1

High-throughput

0.536

High

1315349

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

1

High-throughput

0.536

High

254386

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.513

High

598749

ANFB
Natriuretic peptides B

1

0

High-throughput

0.513

High

983309

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

1242594

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1310214

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1315339

CC74A
Coiled-coil domain-containing protein 74A

1

1

High-throughput

0.489

High

242240

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

882770

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

1315346

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

282003

MPPB
Mitochondrial-processing peptidase subunit beta

1

0

High-throughput

0.458

High

471125

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

519159

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

532757

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

828846

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841824

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851947

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

1048591

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1106603

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1113648

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1117776

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1142595

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1207068

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1254572

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1315340

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

1315350

TR61B
tRNA

1

0

High-throughput

0.458

High

1315351

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1315352

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1315353

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1315355

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

653429

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1315361

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.426

High

1187844

FX4L6
Forkhead box protein D4-like 6

3

0

High-throughput

0.347

High

1315334

TEFF1
Tomoregulin-1

3

0

High-throughput

0.347

High

124675

PLM
Phospholemman

2

0

High-throughput

0.328

High

171895

ZN263
Zinc finger protein 263

2

0

High-throughput

0.328

High

1279005

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

1307233

TF2LY
Homeobox protein TGIF2LY

2

0

High-throughput

0.328

High

1315335

TRM2A
tRNA

2

0

High-throughput

0.328

High

1315342

ZN414
Zinc finger protein 414

2

0

High-throughput

0.328

High

1315347

GPX7
Glutathione peroxidase 7

2

0

High-throughput

0.328

High

1315354

SIX2
Homeobox protein SIX2

2

0

High-throughput

0.328

High

251935

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

High-throughput

0.279

Low

279417

TULP3
Tubby-related protein 3

1

0

High-throughput

0.279

Low

711570

NK3R
Neuromedin-K receptor

1

0

High-throughput

0.279

Low

754578

S10A3
Protein S100-A3

1

0

High-throughput

0.279

Low

1029516

SRSF2
Serine/arginine-rich splicing factor 2

1

0

High-throughput

0.279

Low

1200313

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.279

Low

1208223

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1286434

DSG4
Desmoglein-4

1

0

High-throughput

0.279

Low

1314954

ELOA2
Elongin-A2

1

0

High-throughput

0.279

Low

1315336

ZN444
Zinc finger protein 444

1

0

High-throughput

0.279

Low

1315337

PSD4
PH and SEC7 domain-containing protein 4

1

0

High-throughput

0.279

Low

1315338

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.279

Low

1315345

UIMC1
BRCA1-A complex subunit RAP80

1

0

High-throughput

0.279

Low

1315357

AT7L1
Ataxin-7-like protein 1

1

0

High-throughput

0.279

Low

1315359

RBMX2
RNA-binding motif protein, X-linked 2

1

0

High-throughput

0.279

Low

1315356

TKNK
Tachykinin-3

1

0

High-throughput

0.269

Low

1315341

SPDLY
Protein Spindly

1

0

High-throughput

0.249

Low

516690

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low

1315344

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low

1315358

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025