Protein: ACEA
Isocitrate lyase (ICL) (EC 4.1.3.1) (Methylisocitrate lyase) (MICA) (EC 4.1.3.30) (Threo-D(S)-isocitrate glyoxylate-lyase)

Gene: ACEA, ICL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 20
UniProt ID: P28240

Gene Ontology (top 5):
GO:0004451 - isocitrate lyase activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005773 - vacuole
GO:0006097 - glyoxylate cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

523251

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

455609

TRPD
Anthranilate phosphoribosyltransferase

1

0

High-throughput

0.493

High

701490

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.493

High

701482

GID4
GID complex substrate-recognition subunit 4

1

0

Small-scale

0.460

High

454710

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

645316

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

701480

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

701481

TOR1
Serine/threonine-protein kinase TOR1

1

0

Small-scale

0.458

High

701483

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

Small-scale

0.458

High

701487

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

544045

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

701489

IMA1
Importin subunit alpha

1

0

High-throughput

0.438

High

381920

H4
Histone H4

2

0

High-throughput

0.307

High

679444

CDC48
Cell division control protein 48

2

0

High-throughput

0.305

High

701486

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.269

Low

701484

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

701485

LST8
Target of rapamycin complex subunit LST8

1

0

Small-scale

0.249

Low

701488

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

701491

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

701492

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025