Protein: TCO89
Target of rapamycin complex 1 subunit TCO89 (TORC1 subunit TCO89) (89 kDa TOR complex 1 protein)

Gene: TCO89
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: Q08921

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0001558 - regulation of cell growth
GO:0005886 - plasma membrane
GO:0006071 - glycerol metabolic process
GO:0007584 - response to nutrient

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

762877

TOR1
Serine/threonine-protein kinase TOR1

6

1

Small-scale

0.733

High

806379

KOG1
Target of rapamycin complex 1 subunit KOG1

6

0

Small-scale

0.702

High

1025797

RAGAB
GTP-binding protein GTR1

2

1

Small-scale

0.633

High

801944

KSP1
Serine/threonine-protein kinase KSP1

2

1

High-throughput

0.621

High

918075

PIB2
Glutamine sensor PIB2

2

0

Small-scale

0.598

High

816011

VAC8
Vacuolar protein 8

2

0

Small-scale

0.569

High

834778

LST8
Target of rapamycin complex subunit LST8

1

0

Small-scale

0.530

High

1065132

IQG1
Ras GTPase-activating-like protein IQG1

1

0

Small-scale

0.529

High

554061

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.513

High

646165

NPR1
Nitrogen permease reactivator protein

1

0

High-throughput

0.513

High

919355

RAGCD
GTP-binding protein GTR2

1

1

Small-scale

0.501

High

1054078

FMP27
Protein FMP27, mitochondrial

1

0

High-throughput

0.493

High

828517

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.489

High

916537

SAP4
SIT4-associating protein SAP4

1

1

High-throughput

0.489

High

918404

FMP48
Probable serine/threonine-protein kinase FMP48

1

1

High-throughput

0.489

High

743426

TOR2
Serine/threonine-protein kinase TOR2

1

1

High-throughput

0.481

High

525428

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.479

High

527917

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.479

High

710025

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

760370

BMH2
Protein BMH2

1

1

High-throughput

0.479

High

1065129

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.460

High

365706

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

553934

WHI2
Growth regulation protein

1

0

Small-scale

0.458

High

580199

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

1051447

PAL1
Protein PAL1

1

0

High-throughput

0.458

High

1052980

VID22
Vacuolar import and degradation protein 22

1

0

High-throughput

0.458

High

1059388

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

546603

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

820023

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

1035173

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

670350

NAP1
Nucleosome assembly protein

4

0

Small-scale

0.358

High

479701

F16P
Fructose-1,6-bisphosphatase

2

0

Small-scale

0.305

High

826905

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

1038825

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

445377

CDC31
Cell division control protein 31

1

0

High-throughput

0.279

Low

722332

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

736057

SP110
Spindle pole body component 110

1

0

High-throughput

0.279

Low

778922

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.279

Low

782478

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

1064853

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.269

Low

763237

PP2C1
Protein phosphatase 2C homolog 1

1

0

High-throughput

0.251

Low

1065130

NBP2
NAP1-binding protein 2

1

0

High-throughput

0.251

Low

366731

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.249

Low

480005

PRTB
Cerevisin

1

0

High-throughput

0.249

Low

534199

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.249

Low

548244

BIK1
Nuclear fusion protein BIK1

1

0

Small-scale

0.249

Low

572661

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.249

Low

644648

MDHC
Malate dehydrogenase, cytoplasmic

1

0

Small-scale

0.249

Low

680132

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

701492

ACEA
Isocitrate lyase

1

0

Small-scale

0.249

Low

708435

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

736527

SFP1
Transcription factor SFP1

1

0

Small-scale

0.249

Low

743651

RTG2
Retrograde regulation protein 2

1

0

High-throughput

0.249

Low

746760

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.249

Low

764169

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

793213

AKL1
Serine/threonine-protein kinase AKL1

1

0

High-throughput

0.249

Low

795251

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

816979

BIM1
Protein BIM1

1

0

Small-scale

0.249

Low

850920

ALK1
Serine/threonine-protein kinase Haspin homolog ALK1

1

0

High-throughput

0.249

Low

863168

FYV8
Protein FYV8

1

0

High-throughput

0.249

Low

918026

PNC1
Nicotinamidase

1

0

High-throughput

0.249

Low

924432

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.249

Low

925308

BOP3
Protein BOP3

1

0

High-throughput

0.249

Low

1044812

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

1065131

CRM2
Homeostatic regulator of DAG

1

0

High-throughput

0.249

Low

1065133

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.249

Low

576017

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

737432

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.232

Low

824577

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low

1059350

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025