Protein: KAPR
cAMP-dependent protein kinase regulatory subunit (cAPK regulatory subunit) (Bypass of cyclase mutations protein 1) (Protein kinase A regulatory subunit) (PKA regulatory subunit)

Gene: KAPR, BCY1
Organism: Saccharomyces cerevisiae S288C
Interactions: 115
UniProt ID: P07278

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

441311

KAPB
cAMP-dependent protein kinase type 2

19

20

Small-scale

0.988

High

440998

KAPA
cAMP-dependent protein kinase type 1

20

20

Small-scale

0.988

High

437863

KAPC
cAMP-dependent protein kinase type 3

11

20

Small-scale

0.977

High

454674

KAPR
cAMP-dependent protein kinase regulatory subunit

5

18

Small-scale

0.920

High

454675

LTE1
Guanine nucleotide exchange factor LTE1

1

2

High-throughput

0.691

High

454690

CSK21
Casein kinase II subunit alpha

1

9

High-throughput

0.691

High

454705

KC11
Casein kinase I homolog 1

1

13

High-throughput

0.691

High

454676

PBS2
MAP kinase kinase PBS2

1

16

High-throughput

0.647

High

454695

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.647

High

454706

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

13

High-throughput

0.647

High

454719

ELM1
Serine/threonine-protein kinase ELM1

1

3

High-throughput

0.647

High

454759

VHS1
Serine/threonine-protein kinase VHS1

1

2

High-throughput

0.647

High

454768

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

7

High-throughput

0.647

High

454689

HSC82
ATP-dependent molecular chaperone HSC82

3

4

Small-scale

0.640

High

454682

HSP71
Heat shock protein SSA1

3

4

Small-scale

0.624

High

454704

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

2

1

High-throughput

0.619

High

454703

RAD53
Serine/threonine-protein kinase RAD53

1

10

High-throughput

0.618

High

454728

AKL1
Serine/threonine-protein kinase AKL1

1

5

High-throughput

0.618

High

454729

SRO77
Lethal(2) giant larvae protein homolog SRO77

2

1

High-throughput

0.590

High

454678

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.586

High

454708

SIS1
Protein SIS1

2

1

High-throughput

0.571

High

454722

HSP78
Heat shock protein 78, mitochondrial

2

1

High-throughput

0.571

High

454698

IRA2
Inhibitory regulator protein IRA2

1

5

Small-scale

0.561

High

454700

MYO2
Myosin-2

1

6

Small-scale

0.561

High

454692

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.559

High

454711

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.551

High

454724

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.541

High

454757

RNT1
Ribonuclease 3

1

1

High-throughput

0.541

High

367854

ENO2
Enolase 2

1

0

Small-scale

0.537

High

454701

HSP60
Heat shock protein 60, mitochondrial

1

0

Small-scale

0.537

High

454726

YPT53
GTP-binding protein YPT53

1

11

High-throughput

0.536

High

454755

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

4

High-throughput

0.536

High

454751

SOK2
Protein SOK2

1

0

High-throughput

0.518

High

454766

TIP41
Type 2A phosphatase activator TIP41

1

0

High-throughput

0.518

High

454733

DHE5
NADP-specific glutamate dehydrogenase 2

1

1

High-throughput

0.515

High

454734

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.515

High

454758

SKI8
Antiviral protein SKI8

1

3

High-throughput

0.515

High

454361

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

454735

PP2C2
Protein phosphatase 2C homolog 2

1

0

High-throughput

0.513

High

454737

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.513

High

454707

PTP1
Tyrosine-protein phosphatase 1

1

10

Small-scale

0.501

High

454750

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

1

High-throughput

0.494

High

454712

EF1G1
Elongation factor 1-gamma 1

1

0

High-throughput

0.493

High

454772

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.493

High

454756

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.489

High

454769

ATG5
Autophagy protein 5

1

0

High-throughput

0.486

High

454679

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

1

11

Small-scale

0.481

High

454749

ZDS1
Protein ZDS1

1

4

Small-scale

0.481

High

392023

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

446196

PHSG
Glycogen phosphorylase

1

4

Small-scale

0.479

High

453351

PYR1
Multifunctional protein URA2

1

4

Small-scale

0.479

High

454680

RL20B
Large ribosomal subunit protein eL20B

1

2

Small-scale

0.479

High

454684

RL4A
Large ribosomal subunit protein uL4A

1

2

Small-scale

0.479

High

454685

PYC1
Pyruvate carboxylase 1

1

4

Small-scale

0.479

High

454694

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

2

Small-scale

0.479

High

454709

SPT5
Transcription elongation factor SPT5

1

1

Small-scale

0.479

High

454713

HS104
Heat shock protein 104

1

1

Small-scale

0.479

High

454715

PYC2
Pyruvate carboxylase 2

1

4

Small-scale

0.479

High

454727

GBLP
Small ribosomal subunit protein RACK1

1

7

Small-scale

0.479

High

454730

ATG8
Autophagy-related protein 8

1

6

High-throughput

0.479

High

454731

FKS1
1,3-beta-glucan synthase component FKS1

1

1

Small-scale

0.479

High

454738

SYA
Alanine--tRNA ligase, mitochondrial

1

1

Small-scale

0.479

High

454742

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

454748

RL4B
Large ribosomal subunit protein uL4B

1

2

Small-scale

0.479

High

454753

CRZ1
Transcriptional regulator CRZ1

1

1

Small-scale

0.479

High

454754

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

Small-scale

0.479

High

454767

RL7B
Large ribosomal subunit protein uL30B

1

1

Small-scale

0.479

High

454771

RL13A
Large ribosomal subunit protein eL13A

1

1

Small-scale

0.479

High

359114

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

Small-scale

0.458

High

364872

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.458

High

365524

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.458

High

401822

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

439190

PDC1
Pyruvate decarboxylase isozyme 1

1

0

Small-scale

0.458

High

450488

FAS1
Fatty acid synthase subunit beta

1

0

Small-scale

0.458

High

454677

GAL7
Galactose-1-phosphate uridylyltransferase

1

0

Small-scale

0.458

High

454681

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

454687

ALF
Fructose-bisphosphate aldolase

1

0

Small-scale

0.458

High

454691

VATB
V-type proton ATPase subunit B

1

0

Small-scale

0.458

High

454697

FAS2
Fatty acid synthase subunit alpha

1

0

Small-scale

0.458

High

454699

ACON
Aconitate hydratase, mitochondrial

1

0

Small-scale

0.458

High

454710

ACEA
Isocitrate lyase

1

0

Small-scale

0.458

High

454714

EF2
Elongation factor 2

1

0

Small-scale

0.458

High

454716

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

454718

GLGB
1,4-alpha-glucan-branching enzyme

1

0

Small-scale

0.458

High

454720

RSSA1
Small ribosomal subunit protein uS2A

1

0

Small-scale

0.458

High

454721

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

454723

RS3A1
Small ribosomal subunit protein eS1A

1

0

Small-scale

0.458

High

454725

TSA1
Peroxiredoxin TSA1

1

0

Small-scale

0.458

High

454732

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

454741

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

Small-scale

0.458

High

454746

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

454747

JHD2
Histone demethylase JHD2

1

0

Small-scale

0.458

High

454760

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

454761

NHEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.458

High

454762

GDE
Glycogen debranching enzyme

1

0

Small-scale

0.458

High

454764

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

454765

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

454770

WHI5
G1-specific transcriptional repressor WHI5

1

0

High-throughput

0.458

High

454683

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

454686

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

454693

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.445

High

454717

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

454736

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

454696

ADT2
ADP,ATP carrier protein 2

1

4

Small-scale

0.437

High

454743

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

2

Small-scale

0.437

High

454752

COPA
Coatomer subunit alpha

1

1

Small-scale

0.437

High

454763

AP3D
AP-3 complex subunit delta

1

5

High-throughput

0.437

High

454702

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

439062

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

Small-scale

0.249

Low

454739

AXL1
Putative protease AXL1

1

0

High-throughput

0.249

Low

454740

CDC1
Cell division control protein 1

1

0

Small-scale

0.249

Low

454744

PRY1
Protein PRY1

1

0

High-throughput

0.249

Low

454688

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

454745

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025