Protein: LST8
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (Lethal with SEC13 protein 8)

Gene: LST8
Organism: Saccharomyces cerevisiae S288C
Interactions: 66
UniProt ID: P41318

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001558 - regulation of cell growth
GO:0005774 - vacuolar membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743397

TOR2
Serine/threonine-protein kinase TOR2

9

15

Small-scale

0.974

High

762832

TOR1
Serine/threonine-protein kinase TOR1

7

15

Small-scale

0.965

High

834776

AVO1
Target of rapamycin complex 2 subunit AVO1

3

0

Small-scale

0.817

High

806297

KOG1
Target of rapamycin complex 1 subunit KOG1

5

19

Small-scale

0.716

High

817728

TSC11
Target of rapamycin complex 2 subunit TSC11

4

5

Small-scale

0.694

High

626776

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.646

High

834777

RTC1
Restriction of telomere capping protein 1

1

17

High-throughput

0.646

High

834773

AVO2
Target of rapamycin complex 2 subunit AVO2

2

5

Small-scale

0.628

High

834766

PIB2
Glutamine sensor PIB2

2

0

Small-scale

0.598

High

367989

ENO2
Enolase 2

2

2

High-throughput

0.588

High

834761

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.578

High

794709

SEA4
SEH-associated protein 4

1

1

High-throughput

0.575

High

834760

LST8
Target of rapamycin complex subunit LST8

1

17

Small-scale

0.575

High

365643

PGK
Phosphoglycerate kinase

2

0

High-throughput

0.563

High

479686

F16P
Fructose-1,6-bisphosphatase

2

0

Small-scale

0.559

High

834764

BIT61
Target of rapamycin complex 2 subunit BIT61

1

2

Small-scale

0.554

High

682312

SPB4
ATP-dependent rRNA helicase SPB4

1

15

High-throughput

0.553

High

646136

NPR1
Nitrogen permease reactivator protein

1

11

High-throughput

0.536

High

801850

KSP1
Serine/threonine-protein kinase KSP1

1

3

High-throughput

0.536

High

828483

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.536

High

834765

SAP4
SIT4-associating protein SAP4

1

1

High-throughput

0.536

High

736518

SFP1
Transcription factor SFP1

2

1

Small-scale

0.533

High

826573

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

834778

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

Small-scale

0.530

High

419770

H2A2
Histone H2A.2

1

6

High-throughput

0.514

High

781751

SET3
SET domain-containing protein 3

1

20

High-throughput

0.514

High

794747

RTG3
Retrograde regulation protein 3

1

0

High-throughput

0.513

High

368696

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.500

High

628074

FKBP
FK506-binding protein 1

1

5

Small-scale

0.489

High

740583

IME2
Meiosis induction protein kinase IME2/SME1

1

9

High-throughput

0.489

High

778904

NNK1
Nitrogen network kinase 1

1

2

High-throughput

0.489

High

834767

FMP48
Probable serine/threonine-protein kinase FMP48

1

2

High-throughput

0.489

High

834772

KU80
ATP-dependent DNA helicase II subunit 2

1

2

High-throughput

0.489

High

644635

MDHC
Malate dehydrogenase, cytoplasmic

1

1

Small-scale

0.479

High

670825

SIS1
Protein SIS1

1

11

High-throughput

0.479

High

834768

APJ1
J domain-containing protein APJ1

1

12

High-throughput

0.479

High

834771

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

534189

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.458

High

746367

RAEP
Rab proteins geranylgeranyltransferase component A

1

0

Small-scale

0.458

High

661646

MPCP
Mitochondrial phosphate carrier protein

1

5

High-throughput

0.457

High

823428

MPM1
Mitochondrial peculiar membrane protein 1

1

1

High-throughput

0.457

High

394652

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

524246

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

592310

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.445

High

734127

EF2
Elongation factor 2

1

6

High-throughput

0.445

High

819002

SSB2
Ribosome-associated molecular chaperone SSB2

1

16

High-throughput

0.445

High

548214

BIK1
Nuclear fusion protein BIK1

1

7

Small-scale

0.437

High

617945

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

4

Small-scale

0.437

High

707364

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

795045

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

815145

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

3

High-throughput

0.437

High

816957

BIM1
Protein BIM1

1

5

Small-scale

0.437

High

575960

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.407

High

694566

SPT5
Transcription elongation factor SPT5

1

8

High-throughput

0.407

High

737410

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

5

High-throughput

0.407

High

834763

STU2
Protein STU2

1

4

High-throughput

0.407

High

834774

BRE1
E3 ubiquitin-protein ligase BRE1

1

14

High-throughput

0.407

High

834762

OSW7
Outer spore wall protein 7

1

0

High-throughput

0.279

Low

382932

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

553922

WHI2
Growth regulation protein

1

0

Small-scale

0.249

Low

639559

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

0

High-throughput

0.249

Low

701485

ACEA
Isocitrate lyase

1

0

Small-scale

0.249

Low

834769

PYP1
Polyol phosphate phosphatase PYP1

1

0

High-throughput

0.249

Low

834775

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

834770

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025