Protein: HRK1
Serine/threonine-protein kinase HRK1 (EC 2.7.11.1) (Hygromycin resistance kinase 1)

Gene: HRK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 92
UniProt ID: Q08732

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

419980

SNF1
Carbon catabolite-derepressing protein kinase

1

19

High-throughput

0.691

High

584812

CSK22
Casein kinase II subunit alpha'

1

19

High-throughput

0.691

High

798394

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.691

High

965506

NOP3
Serine/arginine

1

7

High-throughput

0.691

High

522725

AAKG
5'-AMP-activated protein kinase subunit gamma

3

9

High-throughput

0.662

High

649931

CDC15
Cell division control protein 15

1

18

High-throughput

0.647

High

492688

HSP71
Heat shock protein SSA1

3

17

High-throughput

0.633

High

594371

PP11
Serine/threonine-protein phosphatase PP1-1

2

12

High-throughput

0.621

High

757365

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

6

High-throughput

0.618

High

986484

FKBP4
FK506-binding protein 4

1

6

High-throughput

0.618

High

996277

YRA1
RNA annealing protein YRA1

1

5

High-throughput

0.618

High

367027

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.618

High

694288

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

4

High-throughput

0.618

High

977709

GIS1
Transcriptional activator/repressor GIS1

1

2

High-throughput

0.618

High

979146

GIS4
Protein GIS4

2

1

High-throughput

0.611

High

628550

SIS1
Protein SIS1

1

5

High-throughput

0.575

High

561081

EF3A
Elongation factor 3A

1

4

High-throughput

0.536

High

597913

PWP1
Periodic tryptophan protein 1

1

5

High-throughput

0.536

High

676442

XPO1
Exportin-1

1

5

High-throughput

0.536

High

699741

DRS1
ATP-dependent RNA helicase DRS1

1

6

High-throughput

0.536

High

703131

MRT4
Ribosome assembly factor MRT4

1

3

High-throughput

0.536

High

704440

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.536

High

777329

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.536

High

864623

BRE5
UBP3-associated protein BRE5

1

5

High-throughput

0.536

High

962006

REG1
Resistance to glucose repression protein 1

1

1

High-throughput

0.536

High

973475

NOG1
Nucleolar GTP-binding protein 1

1

2

High-throughput

0.536

High

976880

HAS1
ATP-dependent RNA helicase HAS1

1

8

High-throughput

0.536

High

996273

CUB1

1

1

High-throughput

0.536

High

996278

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

417607

PHSG
Glycogen phosphorylase

1

1

High-throughput

0.501

High

426470

SYSC
Serine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.501

High

554761

HSP26
Heat shock protein 26

1

1

High-throughput

0.501

High

765777

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

10

High-throughput

0.501

High

979658

ASND1
Asparagine synthetase domain-containing protein YML096W

1

1

High-throughput

0.501

High

996275

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

1

High-throughput

0.501

High

972666

SKI8
Antiviral protein SKI8

1

3

High-throughput

0.494

High

549521

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.489

High

693890

SRP40
Suppressor protein SRP40

1

2

High-throughput

0.489

High

733963

RPF2
Ribosome biogenesis protein RPF2

1

2

High-throughput

0.489

High

754214

CIC1
Proteasome-interacting protein CIC1

1

1

High-throughput

0.489

High

776533

RLP7
Ribosome biogenesis protein RLP7

1

3

High-throughput

0.489

High

778879

NOP2
25S rRNA

1

1

High-throughput

0.489

High

837474

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

5

High-throughput

0.489

High

980171

ERB1
Ribosome biogenesis protein ERB1

1

4

High-throughput

0.489

High

992542

NOC3
Nucleolar complex-associated protein 3

1

1

High-throughput

0.489

High

996272

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.489

High

563991

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.480

High

478580

HSP77
Import motor subunit, mitochondrial

1

14

High-throughput

0.479

High

524470

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

701126

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

737231

LONM
Lon protease homolog, mitochondrial

1

5

High-throughput

0.479

High

762628

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

797409

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.458

High

865872

IGO1
mRNA stability protein IGO1

1

0

Small-scale

0.458

High

861559

REXO1
RNA exonuclease 1

1

1

High-throughput

0.457

High

863682

ARE2
Sterol O-acyltransferase 2

1

1

High-throughput

0.457

High

996276

SAS10
Something about silencing protein 10

1

1

High-throughput

0.457

High

368470

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

399656

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.445

High

424754

PYR1
Multifunctional protein URA2

1

5

High-throughput

0.445

High

495177

HSP72
Heat shock protein SSA2

1

17

High-throughput

0.445

High

513028

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

540173

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

2

High-throughput

0.445

High

556346

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.445

High

752402

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.445

High

773780

6P21
6-phosphofructo-2-kinase 1

1

8

High-throughput

0.445

High

785254

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.445

High

796944

GCN20
Protein GCN20

1

2

High-throughput

0.445

High

804863

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.445

High

375530

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.437

High

663547

TF2B
Transcription initiation factor IIB

1

7

High-throughput

0.437

High

730933

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

775885

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

860903

PESC
Pescadillo homolog

1

1

High-throughput

0.437

High

996274

YTM1
Ribosome biogenesis protein YTM1

1

7

High-throughput

0.437

High

501263

MAK16
Protein MAK16

1

0

High-throughput

0.279

Low

633902

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.279

Low

634460

SPB1
27S pre-rRNA

1

0

High-throughput

0.279

Low

715500

RRP1
Ribosomal RNA-processing protein 1

1

0

High-throughput

0.279

Low

731883

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.279

Low

755344

RPF1
Ribosome production factor 1

1

0

High-throughput

0.279

Low

764265

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.279

Low

766721

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.279

Low

859524

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.279

Low

987648

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.279

Low

697802

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

0

High-throughput

0.261

Low

747093

IST2
Increased sodium tolerance protein 2

1

0

High-throughput

0.261

Low

763994

HPH2
Protein HPH2

1

0

High-throughput

0.261

Low

859938

MST27
Multicopy suppressor of SEC21 protein 27

1

0

High-throughput

0.261

Low

745605

YBI6
Uncharacterized protein YBL086C

1

0

High-throughput

0.249

Low

745919

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

768061

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024