Protein: RL28
Large ribosomal subunit protein bL28 (50S ribosomal protein L28)

Gene: RL28, rpmB
Organism: Escherichia coli K-12
Interactions: 165
UniProt ID: P0A7M2

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

492892

TIG
Trigger factor

3

0

Small-scale

0.607

High

492885

RL32
Large ribosomal subunit protein bL32

2

0

High-throughput

0.601

High

492906

DEAD
ATP-dependent RNA helicase DeaD

2

1

High-throughput

0.588

High

492909

RLUC
Ribosomal large subunit pseudouridine synthase C

2

1

High-throughput

0.588

High

492978

RLUB
Ribosomal large subunit pseudouridine synthase B

2

1

High-throughput

0.588

High

492889

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.576

High

492890

SSRP
SsrA-binding protein

2

0

High-throughput

0.576

High

492897

UVRC
UvrABC system protein C

2

0

High-throughput

0.576

High

492929

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.576

High

492952

MUKB
Chromosome partition protein MukB

2

0

High-throughput

0.576

High

492911

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.569

High

365806

RPOD
RNA polymerase sigma factor RpoD

2

0

High-throughput

0.563

High

368945

SYGA
Glycine--tRNA ligase alpha subunit

2

0

High-throughput

0.563

High

490853

HFQ
RNA-binding protein Hfq

2

0

High-throughput

0.563

High

491915

RPPH
RNA pyrophosphohydrolase

2

0

High-throughput

0.563

High

492891

TGT
Queuine tRNA-ribosyltransferase

2

0

High-throughput

0.563

High

492908

ULAR
HTH-type transcriptional regulator UlaR

2

0

High-throughput

0.563

High

492927

YIBL
Uncharacterized protein YibL

2

0

High-throughput

0.563

High

492936

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.563

High

492959

UBIC
Chorismate pyruvate-lyase

2

0

High-throughput

0.563

High

492972

AIDB
Putative acyl-CoA dehydrogenase AidB

2

0

High-throughput

0.563

High

492976

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.563

High

492994

PTNAB
PTS system mannose-specific EIIAB component

2

0

High-throughput

0.563

High

492939

SSB
Single-stranded DNA-binding protein

2

0

High-throughput

0.559

High

493023

YAJL
Protein/nucleic acid deglycase 3

2

0

Small-scale

0.547

High

492974

NAPA
Periplasmic nitrate reductase

2

1

High-throughput

0.537

High

492958

RHLE
ATP-dependent RNA helicase RhlE

1

2

High-throughput

0.536

High

456983

CHEA
Chemotaxis protein CheA

1

0

High-throughput

0.513

High

489259

ACKA
Acetate kinase

1

0

High-throughput

0.513

High

492886

RS18
Small ribosomal subunit protein bS18

1

0

High-throughput

0.513

High

492907

ADHE
Bifunctional aldehyde-alcohol dehydrogenase AdhE

1

0

High-throughput

0.513

High

492922

YFIA
Ribosome-associated inhibitor A

1

0

High-throughput

0.513

High

492934

MOAB
Molybdenum cofactor biosynthesis protein B

1

0

High-throughput

0.513

High

492957

MSYB
Acidic protein MsyB

1

0

High-throughput

0.513

High

492965

MOAE
Molybdopterin synthase catalytic subunit

1

0

High-throughput

0.513

High

492970

FDHD
Sulfur carrier protein FdhD

1

0

High-throughput

0.513

High

492979

YGGL
Uncharacterized protein YggL

1

0

High-throughput

0.513

High

492984

USPC
Universal stress protein C

1

0

High-throughput

0.513

High

492989

FLAV
Flavodoxin 1

1

0

High-throughput

0.513

High

492990

GPMA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

1

0

High-throughput

0.513

High

493011

FADI
3-ketoacyl-CoA thiolase FadI

1

0

High-throughput

0.513

High

493014

YFGD
Uncharacterized protein YfgD

1

0

High-throughput

0.513

High

492918

PDHR
Pyruvate dehydrogenase complex repressor

1

1

High-throughput

0.489

High

492944

MNGR
Mannosyl-D-glycerate transport/metabolism system repressor MngR

1

1

High-throughput

0.489

High

492968

MODF
ABC transporter ATP-binding protein ModF

1

1

High-throughput

0.489

High

493007

INTQ
Putative defective protein IntQ

1

1

High-throughput

0.489

High

493018

RCLR
RCS-specific HTH-type transcriptional activator RclR

1

1

High-throughput

0.489

High

444270

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.484

High

492898

RHLB
ATP-dependent RNA helicase RhlB

1

2

High-throughput

0.484

High

492947

RECQ
ATP-dependent DNA helicase RecQ

1

1

High-throughput

0.484

High

492991

RLMB
23S rRNA

1

1

High-throughput

0.484

High

492902

DARP
Dual-action ribosomal maturation protein DarP

1

0

High-throughput

0.479

High

492921

YFCZ
UPF0381 protein YfcZ

1

0

High-throughput

0.479

High

492969

PQQL
Probable zinc protease PqqL

1

0

High-throughput

0.479

High

492983

YHHX
Uncharacterized oxidoreductase YhhX

1

0

High-throughput

0.479

High

492995

DMSD
Tat proofreading chaperone DmsD

1

0

High-throughput

0.479

High

493000

RLMI
Ribosomal RNA large subunit methyltransferase I

1

0

High-throughput

0.479

High

493009

DCYD
D-cysteine desulfhydrase

1

0

High-throughput

0.479

High

492941

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

1

High-throughput

0.479

High

365861

DPO1
DNA polymerase I

1

0

High-throughput

0.464

High

395063

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.464

High

489282

ACP
Acyl carrier protein

1

0

High-throughput

0.464

High

490238

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.464

High

491526

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

491729

LPXA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

1

0

High-throughput

0.464

High

492055

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.464

High

492162

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.464

High

492887

RNH
Ribonuclease HI

1

0

High-throughput

0.464

High

492893

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.464

High

492896

UVRB
UvrABC system protein B

1

0

High-throughput

0.464

High

492905

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

492917

HSLR
Heat shock protein 15

1

0

High-throughput

0.464

High

492930

MAP1
Methionine aminopeptidase

1

0

High-throughput

0.464

High

492937

SPOT
Bifunctional

1

0

High-throughput

0.464

High

492943

RCSB
Transcriptional regulatory protein RcsB

1

0

High-throughput

0.464

High

492945

SELB
Selenocysteine-specific elongation factor

1

0

High-throughput

0.464

High

492993

NFI
Endonuclease V

1

0

High-throughput

0.464

High

367318

CAPP
Phosphoenolpyruvate carboxylase

1

0

High-throughput

0.458

High

367422

ILVI
Acetolactate synthase isozyme 3 large subunit

1

0

High-throughput

0.458

High

368266

THRC
Threonine synthase

1

0

High-throughput

0.458

High

483692

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

0

High-throughput

0.458

High

489269

LEUC
3-isopropylmalate dehydratase large subunit

1

0

High-throughput

0.458

High

490626

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.458

High

492894

SMRB
Ribosome rescue factor SmrB

1

0

High-throughput

0.458

High

492899

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.458

High

492901

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.458

High

492942

ISCR
HTH-type transcriptional regulator IscR

1

0

High-throughput

0.458

High

492956

TEHB
Tellurite methyltransferase

1

0

High-throughput

0.458

High

492971

YJAG
Uncharacterized protein YjaG

1

0

High-throughput

0.458

High

492992

GMHBB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

1

0

High-throughput

0.458

High

492996

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

493021

MENI
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

1

0

High-throughput

0.458

High

492932

PAEA
Polyamine export protein

1

1

High-throughput

0.457

High

492925

FIMB
Type 1 fimbriae regulatory protein FimB

1

1

High-throughput

0.442

High

492946

TOP3
DNA topoisomerase 3

1

1

High-throughput

0.442

High

492985

TORZ
Trimethylamine-N-oxide reductase 2

1

1

High-throughput

0.437

High

493010

YEGH
UPF0053 protein YegH

1

1

High-throughput

0.437

High

491578

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.426

High

492950

RNE
Ribonuclease E

1

0

Small-scale

0.426

High

492964

THIG
Thiazole synthase

1

0

High-throughput

0.426

High

493004

PAAX
Transcriptional repressor PaaX

3

0

High-throughput

0.342

High

491780

MOAC
Cyclic pyranopterin monophosphate synthase

2

0

High-throughput

0.319

High

492951

RECJ
Single-stranded-DNA-specific exonuclease RecJ

2

0

High-throughput

0.313

High

493016

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

2

0

High-throughput

0.313

High

492895

YACL
UPF0231 protein YacL

2

0

High-throughput

0.307

High

492916

MBHM
Hydrogenase-2 large chain

2

0

High-throughput

0.307

High

492960

HOLB
DNA polymerase III subunit delta'

2

0

High-throughput

0.307

High

492962

HOLC
DNA polymerase III subunit chi

2

0

High-throughput

0.307

High

492967

3PASE
Inorganic triphosphatase

2

0

High-throughput

0.307

High

492982

YRAN
UPF0102 protein YraN

2

0

High-throughput

0.307

High

492986

END8
Endonuclease 8

2

0

High-throughput

0.307

High

492998

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.307

High

493015

A2MG
Alpha-2-macroglobulin

2

0

High-throughput

0.307

High

393933

ARAF
L-arabinose-binding periplasmic protein

1

0

High-throughput

0.279

Low

489421

ATPE
ATP synthase epsilon chain

1

0

High-throughput

0.279

Low

492910

WZB
Low molecular weight protein-tyrosine-phosphatase Wzb

1

0

High-throughput

0.279

Low

492915

FLIL
Flagellar protein FliL

1

0

High-throughput

0.279

Low

492919

RUTR
HTH-type transcriptional regulator RutR

1

0

High-throughput

0.279

Low

492924

ILVM
Acetolactate synthase isozyme 2 small subunit

1

0

High-throughput

0.279

Low

492926

YHJR
Protein YhjR

1

0

High-throughput

0.279

Low

492931

AROM
Protein AroM

1

0

High-throughput

0.279

Low

492933

MAZE
Antitoxin MazE

1

0

High-throughput

0.279

Low

492935

NAGC
DNA-binding transcriptional dual regulator NagC

1

0

High-throughput

0.279

Low

492940

THIL
Thiamine-monophosphate kinase

1

0

High-throughput

0.279

Low

492949

TOLA
Tol-Pal system protein TolA

1

0

High-throughput

0.279

Low

492954

MANB
Phosphomannomutase

1

0

High-throughput

0.279

Low

492980

YJJU
Uncharacterized protein YjjU

1

0

High-throughput

0.279

Low

492987

MNGB
Mannosylglycerate hydrolase

1

0

High-throughput

0.279

Low

492988

YIFN
Putative uncharacterized protein YifN

1

0

High-throughput

0.279

Low

492997

YKFJ
Putative uncharacterized protein YkfJ

1

0

High-throughput

0.279

Low

492999

MACA
Macrolide export protein MacA

1

0

High-throughput

0.279

Low

493002

YMGC
Uncharacterized protein YmgC

1

0

High-throughput

0.279

Low

493006

YDFW
Protein YdfW

1

0

High-throughput

0.279

Low

493012

YPEA
Acetyltransferase YpeA

1

0

High-throughput

0.279

Low

493019

FLXA
Protein FlxA

1

0

High-throughput

0.279

Low

493020

YBCM
Uncharacterized HTH-type transcriptional regulator YbcM

1

0

High-throughput

0.279

Low

493022

YGCO
Ferredoxin-like protein YgcO

1

0

High-throughput

0.279

Low

492888

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.261

Low

492900

YCJF
UPF0283 membrane protein YcjF

1

0

High-throughput

0.261

Low

492920

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.261

Low

492923

NLPD
Murein hydrolase activator NlpD

1

0

High-throughput

0.261

Low

492928

YGGE
Uncharacterized protein YggE

1

0

High-throughput

0.261

Low

492953

ARPA
Ankyrin repeat protein A

1

0

High-throughput

0.261

Low

492955

HYPD
Hydrogenase maturation factor HypD

1

0

High-throughput

0.261

Low

493013

YFFL
Uncharacterized protein YffL

1

0

High-throughput

0.261

Low

492021

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.253

Low

492961

HOLD
DNA polymerase III subunit psi

1

0

High-throughput

0.253

Low

492973

LLDD
L-lactate dehydrogenase

1

0

High-throughput

0.253

Low

492903

YBGC
Acyl-CoA thioester hydrolase YbgC

1

0

High-throughput

0.249

Low

492904

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.249

Low

492912

YBIS
Probable L,D-transpeptidase YbiS

1

0

High-throughput

0.249

Low

492913

ATPG
ATP synthase gamma chain

1

0

High-throughput

0.249

Low

492914

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.249

Low

492938

SMP
Probable inner membrane protein Smp

1

0

High-throughput

0.249

Low

492948

PHNK
Putative phosphonates utilization ATP-binding protein PhnK

1

0

High-throughput

0.249

Low

492963

HYPF
Carbamoyltransferase HypF

1

0

High-throughput

0.249

Low

492966

YAFC
Uncharacterized HTH-type transcriptional regulator YafC

1

0

High-throughput

0.249

Low

492975

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

0

High-throughput

0.249

Low

492977

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

492981

KDSD
Arabinose 5-phosphate isomerase KdsD

1

0

High-throughput

0.249

Low

493001

CLSC
Cardiolipin synthase C

1

0

High-throughput

0.249

Low

493003

PAAK
Phenylacetate-coenzyme A ligase

1

0

High-throughput

0.249

Low

493005

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low

493008

YEAO
Uncharacterized protein YeaO

1

0

High-throughput

0.249

Low

493017

GTRB
Prophage bactoprenol glucosyl transferase homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025