Protein: RL23
Large ribosomal subunit protein uL23 (50S ribosomal protein L23)

Gene: RL23, rplW
Organism: Escherichia coli K-12
Interactions: 108
UniProt ID: P0ADZ0

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0019843 - rRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

493037

RL29
Large ribosomal subunit protein uL29

3

0

High-throughput

0.796

High

494941

TIG
Trigger factor

2

0

High-throughput

0.635

High

494272

RS5
Small ribosomal subunit protein uS5

2

0

High-throughput

0.601

High

384025

RL15
Large ribosomal subunit protein uL15

2

0

High-throughput

0.576

High

492435

RL11
Large ribosomal subunit protein uL11

2

0

High-throughput

0.576

High

492496

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.576

High

492602

RL19
Large ribosomal subunit protein bL19

2

0

High-throughput

0.576

High

492724

RL1
Large ribosomal subunit protein uL1

2

0

High-throughput

0.576

High

492929

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.576

High

493153

RL9
Large ribosomal subunit protein bL9

2

0

High-throughput

0.576

High

493904

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.576

High

499923

RL6
Large ribosomal subunit protein uL6

2

0

High-throughput

0.576

High

499944

RSGA
Small ribosomal subunit biogenesis GTPase RsgA

2

0

High-throughput

0.576

High

499955

RL24
Large ribosomal subunit protein uL24

2

0

High-throughput

0.576

High

499956

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.576

High

499958

RL5
Large ribosomal subunit protein uL5

2

0

High-throughput

0.576

High

499961

RL25
Large ribosomal subunit protein bL25

2

0

High-throughput

0.576

High

473276

DNAJ
Chaperone protein DnaJ

2

0

High-throughput

0.563

High

492379

RL10
Large ribosomal subunit protein uL10

2

0

High-throughput

0.563

High

493092

RL33
Large ribosomal subunit protein bL33

2

0

High-throughput

0.563

High

494612

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.563

High

496676

NAPD
Chaperone NapD

2

0

High-throughput

0.563

High

497083

DEAD
ATP-dependent RNA helicase DeaD

2

0

High-throughput

0.563

High

497490

RL13
Large ribosomal subunit protein uL13

2

0

High-throughput

0.563

High

498575

DPS
DNA protection during starvation protein

2

0

High-throughput

0.563

High

499922

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.563

High

499925

RL18
Large ribosomal subunit protein uL18

2

0

High-throughput

0.563

High

499932

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase PssA

2

0

High-throughput

0.563

High

499953

RL2
Large ribosomal subunit protein uL2

2

0

High-throughput

0.563

High

431295

PTRA
Protease 3

1

0

High-throughput

0.513

High

494709

RUVA
Holliday junction branch migration complex subunit RuvA

1

0

High-throughput

0.513

High

499930

SRMB
ATP-dependent RNA helicase SrmB

1

1

High-throughput

0.484

High

496866

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

0

High-throughput

0.464

High

498269

ACCA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

1

0

High-throughput

0.464

High

499918

GYRB
DNA gyrase subunit B

1

0

High-throughput

0.464

High

499927

SECA
Protein translocase subunit SecA

1

0

High-throughput

0.464

High

499931

RNE
Ribonuclease E

1

0

High-throughput

0.464

High

499939

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.464

High

499942

USPG
Universal stress protein UP12

1

0

High-throughput

0.464

High

499949

TSAC
Threonylcarbamoyl-AMP synthase

1

0

High-throughput

0.464

High

499954

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.464

High

499957

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

499963

GNGF
Putative gluconeogenesis factor

1

0

High-throughput

0.464

High

492831

RL20
Large ribosomal subunit protein bL20

1

0

High-throughput

0.458

High

493072

RL32
Large ribosomal subunit protein bL32

1

0

High-throughput

0.458

High

495207

SMRB
Ribosome rescue factor SmrB

1

0

High-throughput

0.458

High

495992

DARP
Dual-action ribosomal maturation protein DarP

1

0

High-throughput

0.458

High

498936

GSTB
Glutathione S-transferase GstB

1

0

High-throughput

0.458

High

499921

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.458

High

499924

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.458

High

499937

TORD
Chaperone protein TorD

1

0

High-throughput

0.458

High

499965

PTFX1
Multiphosphoryl transfer protein 1

1

0

High-throughput

0.458

High

395156

UVRD
DNA helicase II

1

1

High-throughput

0.442

High

490963

IHFB
Integration host factor subunit beta

1

1

High-throughput

0.442

High

499052

DBHA
DNA-binding protein HU-alpha

1

1

High-throughput

0.437

High

491623

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.426

High

496033

YBGC
Acyl-CoA thioester hydrolase YbgC

2

0

High-throughput

0.318

High

499919

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.313

High

492236

PYRH
Uridylate kinase

2

0

High-throughput

0.307

High

497408

CSPC
Cold shock-like protein CspC

2

0

High-throughput

0.307

High

498165

END3
Endonuclease III

2

0

High-throughput

0.307

High

499929

RNR
Ribonuclease R

2

0

High-throughput

0.307

High

499952

ABPB
Anti-bacteriophage protein B

2

0

High-throughput

0.307

High

449933

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.279

Low

490592

ENO
Enolase

1

0

High-throughput

0.279

Low

496773

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.279

Low

498025

YBEL
Uncharacterized protein YbeL

1

0

High-throughput

0.279

Low

499479

YDIE
Uncharacterized protein YdiE

1

0

High-throughput

0.279

Low

499934

TRMO
tRNA

1

0

High-throughput

0.279

Low

499945

YJGL
Uncharacterized protein YjgL

1

0

High-throughput

0.279

Low

499948

GARD
Galactarate dehydratase

1

0

High-throughput

0.279

Low

499967

YGCN
Probable electron transfer flavoprotein-quinone oxidoreductase YgcN

1

0

High-throughput

0.279

Low

499455

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.261

Low

499628

NLPD
Murein hydrolase activator NlpD

1

0

High-throughput

0.261

Low

499917

CPXP
Periplasmic protein CpxP

1

0

High-throughput

0.261

Low

499938

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

0

High-throughput

0.261

Low

499946

NANM
N-acetylneuraminate epimerase

1

0

High-throughput

0.261

Low

499950

YHHX
Uncharacterized oxidoreductase YhhX

1

0

High-throughput

0.261

Low

499960

YQJI
Transcriptional regulator YqjI

1

0

High-throughput

0.261

Low

395082

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.253

Low

460397

SYL
Leucine--tRNA ligase

1

0

High-throughput

0.253

Low

490705

FIS
DNA-binding protein Fis

1

0

High-throughput

0.253

Low

494662

RPOZ
DNA-directed RNA polymerase subunit omega

1

0

High-throughput

0.253

Low

498201

ATPG
ATP synthase gamma chain

1

0

High-throughput

0.253

Low

498552

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.253

Low

498943

DNAB
Replicative DNA helicase DnaB

1

0

High-throughput

0.253

Low

499915

MAP1
Methionine aminopeptidase

1

0

High-throughput

0.253

Low

499926

RCSA
Transcriptional regulatory protein RcsA

1

0

High-throughput

0.253

Low

499928

SRLR
Glucitol operon repressor

1

0

High-throughput

0.253

Low

499933

YICC
Endoribonuclease YicC

1

0

High-throughput

0.253

Low

404587

UMUC
Protein UmuC

1

0

High-throughput

0.249

Low

494790

SSRP
SsrA-binding protein

1

0

High-throughput

0.249

Low

495565

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.249

Low

498639

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.249

Low

499752

YIDH
Inner membrane protein YidH

1

0

High-throughput

0.249

Low

499916

PAEA
Polyamine export protein

1

0

High-throughput

0.249

Low

499920

OPPB
Oligopeptide transport system permease protein OppB

1

0

High-throughput

0.249

Low

499935

YJAG
Uncharacterized protein YjaG

1

0

High-throughput

0.249

Low

499936

SFGH2
S-formylglutathione hydrolase YeiG

1

0

High-throughput

0.249

Low

499940

YHJD
Inner membrane protein YhjD

1

0

High-throughput

0.249

Low

499941

YHJG
AsmA family protein YhjG

1

0

High-throughput

0.249

Low

499943

AG43
Antigen 43

1

0

High-throughput

0.249

Low

499947

YJJU
Uncharacterized protein YjjU

1

0

High-throughput

0.249

Low

499951

TORZ
Trimethylamine-N-oxide reductase 2

1

0

High-throughput

0.249

Low

499959

YQJD
Uncharacterized protein YqjD

1

0

High-throughput

0.249

Low

499962

MBHS
Hydrogenase-1 small chain

1

0

High-throughput

0.249

Low

499964

YEEJ
Inverse autotransporter adhesin YeeJ

1

0

High-throughput

0.249

Low

499966

MENI
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025