Protein: RL16
Large ribosomal subunit protein uL16 (50S ribosomal protein L16)

Gene: RL16, rplP
Organism: Escherichia coli K-12
Interactions: 64
UniProt ID: P0ADY7

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000049 - tRNA binding
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

497082

DEAD
ATP-dependent RNA helicase DeaD

2

1

High-throughput

0.588

High

494563

RNPA
Ribonuclease P protein component

2

0

High-throughput

0.576

High

491937

RPPH
RNA pyrophosphohydrolase

2

0

High-throughput

0.563

High

494611

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.563

High

495814

RPOC
DNA-directed RNA polymerase subunit beta'

2

0

High-throughput

0.563

High

499896

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

2

0

High-throughput

0.563

High

491622

KPRS
Ribose-phosphate pyrophosphokinase

2

0

High-throughput

0.547

High

497619

RLUC
Ribosomal large subunit pseudouridine synthase C

2

1

High-throughput

0.537

High

492723

RL1
Large ribosomal subunit protein uL1

1

2

High-throughput

0.536

High

493903

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

494080

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

494375

RS8
Small ribosomal subunit protein uS8

1

0

High-throughput

0.513

High

495151

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.513

High

496533

GLN1B
Glutamine synthetase

1

0

High-throughput

0.513

High

495991

DARP
Dual-action ribosomal maturation protein DarP

1

0

High-throughput

0.479

High

497200

FTSE
Cell division ATP-binding protein FtsE

1

0

High-throughput

0.464

High

498935

GSTB
Glutathione S-transferase GstB

1

0

High-throughput

0.458

High

499593

KPYK1
Pyruvate kinase I

1

0

High-throughput

0.458

High

499909

RLMI
Ribosomal RNA large subunit methyltransferase I

1

0

High-throughput

0.458

High

499903

RLUB
Ribosomal large subunit pseudouridine synthase B

1

1

High-throughput

0.437

High

499912

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

2

0

High-throughput

0.313

High

368955

SYGA
Glycine--tRNA ligase alpha subunit

2

0

High-throughput

0.307

High

495272

YACL
UPF0231 protein YacL

2

0

High-throughput

0.307

High

496720

PHOL
PhoH-like protein

2

0

High-throughput

0.307

High

499893

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

2

0

High-throughput

0.307

High

499895

RNR
Ribonuclease R

2

0

High-throughput

0.307

High

499566

YFCZ
UPF0381 protein YfcZ

1

0

High-throughput

0.279

Low

499818

YGIC
Putative acid--amine ligase YgiC

1

0

High-throughput

0.279

Low

499890

NUSA
Transcription termination/antitermination protein NusA

1

0

High-throughput

0.279

Low

499897

ROXA
Ribosomal protein uL16 3-hydroxylase

1

0

High-throughput

0.279

Low

499907

KGUA
Guanylate kinase

1

0

High-throughput

0.279

Low

499911

MTFA
Mlc titration factor A

1

0

High-throughput

0.279

Low

497984

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.261

Low

498324

FTSW
Probable peptidoglycan glycosyltransferase FtsW

1

0

High-throughput

0.261

Low

499454

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.261

Low

499891

NUSG
Transcription termination/antitermination protein NusG

1

0

High-throughput

0.261

Low

499899

OTSA
Trehalose-6-phosphate synthase

1

0

High-throughput

0.261

Low

499904

NANM
N-acetylneuraminate epimerase

1

0

High-throughput

0.261

Low

499906

YHHX
Uncharacterized oxidoreductase YhhX

1

0

High-throughput

0.261

Low

395081

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.253

Low

490342

HSLU
ATP-dependent protease ATPase subunit HslU

1

0

High-throughput

0.253

Low

490962

IHFB
Integration host factor subunit beta

1

0

High-throughput

0.253

Low

491492

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

1

0

High-throughput

0.253

Low

499894

RCSA
Transcriptional regulatory protein RcsA

1

0

High-throughput

0.253

Low

499898

HOLA
DNA polymerase III subunit delta

1

0

High-throughput

0.253

Low

393880

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.249

Low

483709

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

0

High-throughput

0.249

Low

495564

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.249

Low

495970

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.249

Low

496032

YBGC
Acyl-CoA thioester hydrolase YbgC

1

0

High-throughput

0.249

Low

496056

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.249

Low

496392

GLPC
Anaerobic glycerol-3-phosphate dehydrogenase subunit C

1

0

High-throughput

0.249

Low

498739

KDSC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC

1

0

High-throughput

0.249

Low

499889

NSRR
HTH-type transcriptional repressor NsrR

1

0

High-throughput

0.249

Low

499892

OPPB
Oligopeptide transport system permease protein OppB

1

0

High-throughput

0.249

Low

499900

TKT2
Transketolase 2

1

0

High-throughput

0.249

Low

499901

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

0

High-throughput

0.249

Low

499902

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

499905

KDSD
Arabinose 5-phosphate isomerase KdsD

1

0

High-throughput

0.249

Low

499908

GMHBB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

1

0

High-throughput

0.249

Low

499910

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low

499913

YBAY
Uncharacterized lipoprotein YbaY

1

0

High-throughput

0.249

Low

499914

MENI
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

1

0

High-throughput

0.249

Low

494940

TIG
Trigger factor

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025