Protein: APN2
DNA-(apurinic or apyrimidinic site) endonuclease 2 (EC 3.1.11.2) (AP endonuclease 2) (Apurinic-apyrimidinic endonuclease 2)

Gene: APN2
Organism: Saccharomyces cerevisiae S288C
Interactions: 17
UniProt ID: P38207

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 - endonuclease activity
GO:0005634 - nucleus
GO:0006284 - base-excision repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

586450

PCNA
Proliferating cell nuclear antigen

4

3

Small-scale

0.685

High

796005

APN2
DNA-(apurinic or apyrimidinic site) endonuclease 2

1

0

Small-scale

0.546

High

796008

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.493

High

392622

HSP82
ATP-dependent molecular chaperone HSP82

1

2

Small-scale

0.479

High

481598

HSP73
Heat shock protein SSA3

1

4

Small-scale

0.479

High

523728

HSP71
Heat shock protein SSA1

1

4

Small-scale

0.479

High

526507

HSP72
Heat shock protein SSA2

1

4

Small-scale

0.479

High

645725

HSP74
Heat shock protein SSA4

1

4

Small-scale

0.479

High

675941

MAS5
Mitochondrial protein import protein MAS5

1

0

Small-scale

0.458

High

544620

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

395239

GCN4
General control transcription factor GCN4

1

0

High-throughput

0.438

High

792776

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

579273

HSC82
ATP-dependent molecular chaperone HSC82

1

2

Small-scale

0.437

High

796007

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.426

High

796006

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

736551

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025