Protein: HTL1
High temperature lethal protein 1 (Chromatin structure-remodeling complex protein HTL1)

Gene: HTL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: Q9URQ5

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0006337 - nucleosome disassembly
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743159

STH1
Nuclear protein STH1/NPS1

7

2

Small-scale

0.746

High

850611

RSC8
Chromatin structure-remodeling complex protein RSC8

8

0

Small-scale

0.716

High

1061394

RSC58
Chromatin structure-remodeling complex protein RSC58

5

0

High-throughput

0.676

High

1035363

RSC4
Chromatin structure-remodeling complex subunit RSC4

4

3

High-throughput

0.673

High

1055397

RSC2
Chromatin structure-remodeling complex subunit RSC2

4

4

Small-scale

0.673

High

919708

RT102
Regulator of Ty1 transposition protein 102

4

0

High-throughput

0.667

High

745638

RSC7
Chromatin structure-remodeling complex subunit RSC7

4

0

High-throughput

0.658

High

1056363

RSC3
Chromatin structure-remodeling complex protein RSC3

3

1

Small-scale

0.650

High

1054048

SFH1
Chromatin structure-remodeling complex subunit SFH1

3

0

Small-scale

0.622

High

678360

RSC6
Chromatin structure-remodeling complex protein RSC6

3

0

High-throughput

0.616

High

1041017

RSC9
Chromatin structure-remodeling complex subunit RSC9

3

0

High-throughput

0.616

High

382442

H4
Histone H4

3

0

Small-scale

0.613

High

739840

SPT16
FACT complex subunit SPT16

2

0

High-throughput

0.576

High

1050610

ARP9
Actin-like protein ARP9

2

0

High-throughput

0.576

High

1084891

ARP7
Actin-related protein 7

2

0

High-throughput

0.576

High

804017

RSC30
Chromatin structure-remodeling complex protein RSC30

2

1

High-throughput

0.571

High

918537

RSC1
Chromatin structure-remodeling complex subunit RSC1

2

4

High-throughput

0.571

High

454772

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

High-throughput

0.493

High

725951

PSK1
Serine/threonine-protein kinase PSK1

1

0

High-throughput

0.493

High

796008

APN2
DNA-(apurinic or apyrimidinic site) endonuclease 2

1

0

High-throughput

0.493

High

813682

DHE5
NADP-specific glutamate dehydrogenase 2

1

0

High-throughput

0.493

High

1046580

URC2
Uracil catabolism protein 2

1

0

High-throughput

0.493

High

963830

H3
Histone H3

1

0

Small-scale

0.480

High

734509

BTAF1
TATA-binding protein-associated factor MOT1

1

3

Small-scale

0.479

High

777151

BDF1
Bromodomain-containing factor 1

1

1

High-throughput

0.479

High

794249

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

1

High-throughput

0.479

High

1085043

H2AZ
Histone H2A.Z

1

1

Small-scale

0.479

High

381333

H2B1
Histone H2B.1

1

0

High-throughput

0.458

High

419538

H2A1
Histone H2A.1

1

0

High-throughput

0.458

High

449041

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

741209

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

744370

CHD1
Chromo domain-containing protein 1

1

0

High-throughput

0.458

High

764050

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

796046

LDB7
Chromatin structure-remodeling complex protein RSC14

1

0

High-throughput

0.458

High

823071

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.458

High

1040038

HOS3
Histone deacetylase HOS3

1

0

High-throughput

0.458

High

1044533

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

1054175

PDP3
NuA3 HAT complex component PDP3

1

0

High-throughput

0.458

High

1084231

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.458

High

1084483

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

528166

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

546958

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

458969

LYS2
L-2-aminoadipate reductase

1

0

High-throughput

0.269

Low

1062772

NBA1
Protein NBA1

1

0

High-throughput

0.269

Low

1084675

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.269

Low

1404052

TRS33
Trafficking protein particle complex subunit 33

1

0

High-throughput

0.269

Low

825793

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.249

Low

358391

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

395055

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

432754

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.232

Low

450668

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

580342

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

639102

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.232

Low

747674

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025