Protein: NSE5
Non-structural maintenance of chromosome element 5 (Non-SMC element 5)

Gene: NSE5
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: Q03718

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0030915 - Smc5-Smc6 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1043851

SMC6
Structural maintenance of chromosomes protein 6

7

1

Small-scale

0.952

High

817310

KRE29
DNA repair protein KRE29

11

0

Small-scale

0.934

High

1043846

SMC5
Structural maintenance of chromosomes protein 5

5

1

Small-scale

0.925

High

1043848

SMT3
Ubiquitin-like protein SMT3

5

0

Small-scale

0.679

High

805986

RT107
Regulator of Ty1 transposition protein 107

3

0

Small-scale

0.633

High

801137

NSE2
E3 SUMO-protein ligase MMS21

3

0

Small-scale

0.630

High

745495

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

2

0

Small-scale

0.587

High

897496

UBC9
SUMO-conjugating enzyme UBC9

2

0

Small-scale

0.587

High

1043847

SIZ2
E3 SUMO-protein ligase SIZ2

2

1

Small-scale

0.576

High

815662

LIS1
Nuclear distribution protein PAC1

1

0

High-throughput

0.518

High

916742

UFD1
Ubiquitin fusion degradation protein 1

1

0

High-throughput

0.518

High

1043849

SWM1
Anaphase-promoting complex subunit SWM1

1

0

High-throughput

0.518

High

845906

NSE4
Non-structural maintenance of chromosome element 4

1

0

High-throughput

0.513

High

1043841

SIZ1
E3 SUMO-protein ligase SIZ1

1

1

Small-scale

0.481

High

742299

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

742937

HSP79
Heat shock protein homolog SSE2

1

1

High-throughput

0.445

High

448332

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.438

High

454547

PPR1
Pyrimidine pathway regulatory protein 1

1

0

High-throughput

0.438

High

624467

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.438

High

636477

ACE2
Metallothionein expression activator

1

0

High-throughput

0.438

High

924963

NIS1
Protein NIS1

1

0

High-throughput

0.438

High

1042299

TFB3
RNA polymerase II transcription factor B subunit 3

1

0

High-throughput

0.438

High

416913

CDC25
Cell division control protein 25

1

0

High-throughput

0.426

High

678999

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.426

High

736776

ASF2
Anti-silencing protein 2

1

0

High-throughput

0.426

High

796007

APN2
DNA-(apurinic or apyrimidinic site) endonuclease 2

1

0

High-throughput

0.426

High

823118

PPAL
Low molecular weight phosphotyrosine protein phosphatase

1

0

High-throughput

0.426

High

886203

NU145
Nucleoporin NUP145

1

0

High-throughput

0.426

High

1043844

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.426

High

793656

ARL1
ADP-ribosylation factor-like protein 1

1

0

High-throughput

0.282

High

858518

STB2
Protein STB2

1

0

High-throughput

0.282

High

1043845

CENPO
Inner kinetochore subunit MCM21

1

0

High-throughput

0.282

High

808218

IPT1
Inositolphosphotransferase 1

1

0

High-throughput

0.238

Low

808498

ASPG1
L-asparaginase 1

1

0

High-throughput

0.238

Low

863381

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

0

High-throughput

0.238

Low

1040509

GIP3
GLC7-interacting protein 3

1

0

High-throughput

0.238

Low

1043842

YM13A
Transposon Ty1-MR1 Gag polyprotein

1

0

High-throughput

0.238

Low

1043843

NUP59
Nucleoporin ASM4

1

0

High-throughput

0.238

Low

1043850

LPX1
Peroxisomal membrane protein LPX1

1

0

High-throughput

0.238

Low

460362

SYV
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

631991

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025