Protein: PUR4
Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)

Gene: PUR4, ADE6
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: P38972

Gene Ontology (top 5):
GO:0004642 - phosphoribosylformylglycinamidine synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006164 - purine nucleotide biosynthetic process
GO:0006189 - 'de novo' IMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

579384

HSC82
ATP-dependent molecular chaperone HSC82

3

1

High-throughput

0.633

High

808436

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

523943

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.552

High

808439

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

1

High-throughput

0.515

High

392727

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

750658

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

808441

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

808443

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

808447

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

623856

MYO2
Myosin-2

1

0

Small-scale

0.460

High

572579

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

734979

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

737858

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

795342

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

803539

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

808438

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

808440

ESP1
Separin

1

0

High-throughput

0.458

High

808444

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

808446

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

510486

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.445

High

526691

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

544866

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

675997

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

727024

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741577

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

742849

HSP79
Heat shock protein homolog SSE2

1

4

High-throughput

0.445

High

808435

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

670701

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

592246

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

808437

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.426

High

808442

VAC14
Vacuole morphology and inheritance protein 14

2

0

High-throughput

0.314

High

625010

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.279

Low

700102

PRP45
Pre-mRNA-processing protein 45

1

0

Small-scale

0.251

Low

707090

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

762957

SPT7
SAGA complex subunit SPT7

1

0

High-throughput

0.249

Low

794984

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

806705

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

808445

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025