Protein: RCK2
Serine/threonine-protein kinase RCK2 (EC 2.7.11.1) (CAM kinase-like protein kinase CLK1)

Gene: RCK2
Organism: Saccharomyces cerevisiae S288C
Interactions: 93
UniProt ID: P38623

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

737842

HOG1
Mitogen-activated protein kinase HOG1

12

20

Small-scale

0.981

High

800789

RCK2
Serine/threonine-protein kinase RCK2

2

17

Small-scale

0.768

High

646386

RAD53
Serine/threonine-protein kinase RAD53

2

16

Small-scale

0.754

High

800795

AURK
Aurora kinase

1

17

High-throughput

0.724

High

778932

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

17

High-throughput

0.647

High

800811

FPK1
Flippase kinase 1

1

17

High-throughput

0.647

High

800821

AVO2
Target of rapamycin complex 2 subunit AVO2

1

3

High-throughput

0.647

High

800832

YP150
Putative serine/threonine-protein kinase YPL150W

1

20

High-throughput

0.647

High

526576

HSP72
Heat shock protein SSA2

3

9

High-throughput

0.624

High

448528

RHO1
GTP-binding protein RHO1

1

4

High-throughput

0.618

High

579312

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.618

High

618342

CDC42
Cell division control protein 42

1

5

High-throughput

0.618

High

622940

CSK22
Casein kinase II subunit alpha'

1

20

High-throughput

0.618

High

735490

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

18

High-throughput

0.618

High

800814

CDC14
Tyrosine-protein phosphatase CDC14

1

8

High-throughput

0.618

High

800816

ROD1
Protein ROD1

2

3

Small-scale

0.594

High

800820

PLM2
Protein PLM2

1

0

High-throughput

0.584

High

392657

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

628260

ZRC1
Vacuolar zinc transporter ZRC1

2

1

Small-scale

0.566

High

800797

CAJ1
Protein CAJ1

1

4

High-throughput

0.553

High

544710

SSB1
Ribosome-associated molecular chaperone SSB1

2

10

High-throughput

0.552

High

740151

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.517

High

633462

PP11
Serine/threonine-protein phosphatase PP1-1

1

15

High-throughput

0.515

High

446225

PHSG
Glycogen phosphorylase

1

3

High-throughput

0.501

High

732030

MLF3
Protein MLF3

1

1

High-throughput

0.501

High

744841

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

1

High-throughput

0.501

High

800798

PIK1
Phosphatidylinositol 4-kinase PIK1

1

4

High-throughput

0.501

High

800800

VHS2
Protein VHS2

1

1

High-throughput

0.501

High

800805

ROG3
Protein ROG3

1

3

High-throughput

0.501

High

800831

FAL1
ATP-dependent RNA helicase FAL1

1

4

High-throughput

0.501

High

800833

HSP42
Heat shock protein 42

1

4

High-throughput

0.501

High

800834

YN11A
Transposon Ty1-NL1 Gag polyprotein

1

2

High-throughput

0.501

High

800835

STB3
Protein STB3

1

1

High-throughput

0.501

High

416426

HXKA
Hexokinase-1

1

4

High-throughput

0.500

High

800791

RRM3
ATP-dependent DNA helicase RRM3

1

0

High-throughput

0.480

High

800792

YHT1
PH domain-containing protein YHR131C

1

0

High-throughput

0.480

High

800817

YM44
Uncharacterized protein YMR178W

1

0

High-throughput

0.480

High

800818

ADD37
Alpha1-proteinase inhibitor-degradation deficient protein 37

1

0

High-throughput

0.480

High

800823

YL257
Uncharacterized protein YLR257W

1

0

High-throughput

0.480

High

438294

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.479

High

448308

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

6

High-throughput

0.479

High

458959

LYS2
L-2-aminoadipate reductase

1

1

High-throughput

0.479

High

597126

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

623849

MYO2
Myosin-2

1

6

High-throughput

0.479

High

713613

EF1G1
Elongation factor 1-gamma 1

1

5

High-throughput

0.479

High

735998

SP110
Spindle pole body component 110

1

3

High-throughput

0.479

High

739137

PRP19
Pre-mRNA-processing factor 19

1

6

High-throughput

0.479

High

750832

PRS6B
26S proteasome regulatory subunit 6B homolog

1

4

High-throughput

0.479

High

760579

TSA1
Peroxiredoxin TSA1

1

2

High-throughput

0.479

High

796391

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

4

High-throughput

0.479

High

800796

ITS3
Phosphatidylinositol 4-phosphate 5-kinase MSS4

1

6

High-throughput

0.479

High

800799

RSP5
E3 ubiquitin-protein ligase RSP5

1

13

High-throughput

0.479

High

800801

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

1

High-throughput

0.479

High

800802

AGE2
ADP-ribosylation factor GTPase-activating protein effector protein 2

1

13

High-throughput

0.479

High

800809

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

800812

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

1

1

High-throughput

0.479

High

800827

FRA1
Putative Xaa-Pro aminopeptidase FRA1

1

1

High-throughput

0.479

High

800829

CDC53
Cell division control protein 53

1

12

High-throughput

0.479

High

800830

MLH3
DNA mismatch repair protein MLH3

1

2

High-throughput

0.479

High

558694

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

800794

ASPG1
L-asparaginase 1

1

0

High-throughput

0.458

High

800810

SPC98
Spindle pole body component SPC98

1

0

High-throughput

0.458

High

600683

SEC2
Rab guanine nucleotide exchange factor SEC2

1

2

High-throughput

0.457

High

797143

AIM3
Altered inheritance of mitochondria protein 3

1

3

High-throughput

0.457

High

800790

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

12

High-throughput

0.457

High

800837

VCX1
Vacuolar calcium ion transporter

1

1

High-throughput

0.457

High

800815

UBC7
Ubiquitin-conjugating enzyme E2 7

1

5

High-throughput

0.457

High

405084

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.457

High

523803

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

746703

TRS65
Trafficking protein particle complex II-specific subunit 65

1

1

Small-scale

0.439

High

504525

RL31B
Large ribosomal subunit protein eL31B

1

1

High-throughput

0.437

High

706974

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

798412

RGD1
RHO GTPase-activating protein RGD1

1

4

High-throughput

0.437

High

800804

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.437

High

800808

BBC1
Myosin tail region-interacting protein MTI1

1

2

High-throughput

0.437

High

800819

RPN9
26S proteasome regulatory subunit RPN9

1

2

High-throughput

0.437

High

800828

RPN8
26S proteasome regulatory subunit RPN8

1

2

High-throughput

0.437

High

800836

ATG11
Autophagy-related protein 11

2

0

Small-scale

0.325

High

653793

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.292

High

432004

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.279

Low

800793

VPS41
Vacuolar protein sorting-associated protein 41

1

0

High-throughput

0.279

Low

800803

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.279

Low

739528

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

0

High-throughput

0.261

Low

800807

IRC8
Uncharacterized protein IRC8

1

0

High-throughput

0.261

Low

800825

NVJ2
Nucleus-vacuole junction protein 2

1

0

High-throughput

0.261

Low

800826

ACK1
Activator of C kinase protein 1

1

0

High-throughput

0.261

Low

800806

IRC6
Increased recombination centers protein 6

1

0

Small-scale

0.251

Low

444376

HIS7
Imidazoleglycerol-phosphate dehydratase

1

0

High-throughput

0.249

Low

800813

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.249

Low

800822

RTN1
Reticulon-like protein 1

1

0

High-throughput

0.249

Low

800824

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

571829

SNA3
Protein SNA3

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025