Protein: CHO2
Phosphatidylethanolamine N-methyltransferase (PE methyltransferase) (PEAMT) (PEMT) (EC 2.1.1.17) (Choline-requiring protein 2)

Gene: CHO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 24
UniProt ID: P05374

Gene Ontology (top 5):
GO:0004608 - phosphatidylethanolamine N-methyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006656 - phosphatidylcholine biosynthetic process
GO:0032259 - methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

427992

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.518

High

428003

QDR3
Quinidine resistance protein 3

1

0

High-throughput

0.518

High

427997

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

Small-scale

0.458

High

427998

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

427999

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

428006

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

Small-scale

0.458

High

428007

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.458

High

427995

RAD53
Serine/threonine-protein kinase RAD53

1

0

Small-scale

0.261

Low

428012

STE20
Serine/threonine-protein kinase STE20

1

0

Small-scale

0.261

Low

427990

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.249

Low

427991

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.249

Low

427993

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

427994

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

427996

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

428000

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

428001

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

428002

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.249

Low

428005

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

428008

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

428009

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

428010

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

428011

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

428013

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

428004

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025