Protein: CAP
Adenylyl cyclase-associated protein (CAP)

Gene: CAP, SRV2
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P17555

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0007015 - actin filament organization
GO:0007265 - Ras protein signal transduction
GO:0008179 - adenylate cyclase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

605334

ACT
Actin

13

20

Small-scale

0.983

High

605281

CAP
Adenylyl cyclase-associated protein

8

4

Small-scale

0.965

High

475106

CYAA
Adenylate cyclase

9

1

Small-scale

0.757

High

587282

ABP1
Actin-binding protein

10

0

Small-scale

0.726

High

605330

TWF1
Twinfilin-1

3

10

Small-scale

0.664

High

605340

COFI
Cofilin

2

9

High-throughput

0.621

High

605322

SGN1
RNA-binding protein SGN1

2

0

High-throughput

0.595

High

605316

RV167
Reduced viability upon starvation protein 167

2

3

Small-scale

0.590

High

454611

PROF
Profilin

3

2

Small-scale

0.589

High

392186

HSP82
ATP-dependent molecular chaperone HSP82

2

4

High-throughput

0.584

High

605312

TRM5
tRNA

2

0

High-throughput

0.565

High

605325

AIP1
Actin-interacting protein 1

2

0

High-throughput

0.565

High

605333

DNM1
Dynamin-related protein DNM1

1

1

Small-scale

0.552

High

605292

HSP7F
Heat shock protein homolog SSE1

2

2

High-throughput

0.552

High

550743

INO1
Inositol-3-phosphate synthase

1

1

High-throughput

0.541

High

562939

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.541

High

605293

FIMB
Fimbrin

1

2

High-throughput

0.541

High

605310

ARPC1
Actin-related protein 2/3 complex subunit 1

1

1

High-throughput

0.541

High

394205

EF1A
Elongation factor 1-alpha

1

1

Small-scale

0.536

High

605320

SDP1
Dual-specificity protein phosphatase SDP1

1

2

High-throughput

0.536

High

605358

DUF1
DUB-associated factor 1

1

1

High-throughput

0.536

High

605297

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.518

High

605321

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.518

High

605332

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.518

High

605346

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.518

High

569898

RL3
Large ribosomal subunit protein uL3

1

0

Small-scale

0.513

High

604533

PHO81
Phosphate system positive regulatory protein PHO81

1

0

High-throughput

0.513

High

605283

RAD53
Serine/threonine-protein kinase RAD53

1

1

Small-scale

0.501

High

605301

SPT7
SAGA complex subunit SPT7

1

4

High-throughput

0.489

High

605342

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.489

High

605347

UTP13
U3 small nucleolar RNA-associated protein 13

1

1

High-throughput

0.489

High

605294

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.486

High

578792

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

605287

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

605291

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

605282

MYO2
Myosin-2

1

0

Small-scale

0.460

High

149565

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

434797

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

514435

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

605284

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.458

High

605286

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

605296

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

605305

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

605307

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

605309

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

605311

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

605337

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

605341

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

605349

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.458

High

543734

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

591988

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

605299

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

605317

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

605319

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

376209

RAS2
Ras-like protein 2

1

1

High-throughput

0.437

High

605289

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

605290

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

605343

GIS1
Transcriptional activator/repressor GIS1

1

1

High-throughput

0.437

High

605352

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

522979

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

605302

MDJ1
DnaJ homolog 1, mitochondrial

1

0

High-throughput

0.426

High

605326

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

605318

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.407

High

605355

SET6
Potential protein lysine methyltransferase SET6

1

1

High-throughput

0.407

High

605298

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

2

0

High-throughput

0.307

High

605324

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.305

High

605323

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.282

High

605335

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.282

High

605353

YVC1
Calcium channel YVC1

1

0

High-throughput

0.282

High

602105

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.279

Low

605308

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.279

Low

605329

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.279

Low

605351

YD306
F-box protein YDR306C

1

0

High-throughput

0.279

Low

605357

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.279

Low

561411

TBP
TATA-box-binding protein

1

0

High-throughput

0.269

Low

605339

RNT1
Ribonuclease 3

1

0

High-throughput

0.269

Low

383498

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

409917

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433425

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

441685

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

502830

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504020

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512237

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

512796

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

605285

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

605288

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

605295

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

605300

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

605303

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

605304

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

605306

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

605313

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low

605315

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

605327

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

605331

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

605336

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

605344

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

605348

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

605350

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

605354

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

605356

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.249

Low

605314

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

605328

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.232

Low

605338

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.232

Low

605345

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025