Protein: HELD
DNA helicase IV (EC 5.6.2.4) (75 kDa helicase) (DNA 3'-5' helicase IV)

Gene: HELD
Organism: Escherichia coli K-12
Interactions: 36
UniProt ID: P15038

Gene Ontology (top 5):
GO:0000725 - recombinational repair
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

489661

CH60
Chaperonin GroEL

3

2

High-throughput

0.667

High

491126

DNAK
Chaperone protein DnaK

2

2

High-throughput

0.612

High

491440

IF2
Translation initiation factor IF-2

2

4

High-throughput

0.588

High

492516

RL7
Large ribosomal subunit protein bL12

2

1

High-throughput

0.588

High

498284

BCCP
Biotin carboxyl carrier protein of acetyl-CoA carboxylase

2

2

High-throughput

0.588

High

476464

PT1
Phosphoenolpyruvate-protein phosphotransferase

2

0

High-throughput

0.585

High

480592

PFLB
Formate acetyltransferase 1

2

0

High-throughput

0.585

High

578334

GCSP
Glycine dehydrogenase

2

0

High-throughput

0.585

High

368280

CYAA
Adenylate cyclase

1

0

High-throughput

0.567

High

492003

PGK
Phosphoglycerate kinase

2

0

High-throughput

0.563

High

495045

TPIS
Triosephosphate isomerase

2

0

High-throughput

0.563

High

496514

G3P1
Glyceraldehyde-3-phosphate dehydrogenase A

2

0

High-throughput

0.563

High

498239

ATPB
ATP synthase subunit beta

2

0

High-throughput

0.563

High

501234

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.563

High

578337

LIPA
Lipoyl synthase

2

0

High-throughput

0.563

High

578338

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.563

High

578340

DCEB
Glutamate decarboxylase beta

2

0

High-throughput

0.563

High

578341

CSRA
Carbon storage regulator

2

0

High-throughput

0.563

High

506257

EFTU1
Elongation factor Tu 1

2

5

High-throughput

0.558

High

501375

RS1
Small ribosomal subunit protein bS1

2

4

High-throughput

0.537

High

382706

RS7
Small ribosomal subunit protein uS7

1

1

High-throughput

0.536

High

490412

DDLA
D-alanine--D-alanine ligase A

1

2

High-throughput

0.536

High

578336

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.536

High

578343

HSCC
Chaperone protein HscC

1

7

High-throughput

0.536

High

368982

SYGB
Glycine--tRNA ligase beta subunit

1

0

High-throughput

0.513

High

500998

RNK
Regulator of nucleoside diphosphate kinase

1

0

High-throughput

0.513

High

522198

DPO3A
DNA polymerase III subunit alpha

1

0

High-throughput

0.513

High

578339

FLAV
Flavodoxin 1

1

0

High-throughput

0.513

High

578335

PEPB
Peptidase B

1

0

High-throughput

0.493

High

490155

CH10
Co-chaperonin GroES

1

0

High-throughput

0.458

High

506324

EFTU2
Elongation factor Tu 2

1

5

High-throughput

0.457

High

449976

HIS7
Histidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase

1

0

High-throughput

0.279

Low

498418

CYOA
Cytochrome bo(3) ubiquinol oxidase subunit 2

1

0

High-throughput

0.279

Low

498521

MHPB
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase

1

0

High-throughput

0.279

Low

578333

YIDF
Uncharacterized protein YidF

1

0

High-throughput

0.279

Low

578342

FIU
Catecholate siderophore receptor Fiu

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025