Protein: LYS2
L-2-aminoadipate reductase (EC 1.2.1.31) (EC 1.2.1.95) (Alpha-aminoadipate reductase) (Alpha-AR) (L-aminoadipate-semialdehyde dehydrogenase)

Gene: LYS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 23
UniProt ID: P07702

Gene Ontology (top 5):
GO:0004043 - L-aminoadipate-semialdehyde dehydrogenase activity
GO:0005737 - cytoplasm
GO:0019878 - lysine biosynthetic process via aminoadipic acid
GO:0031177 - phosphopantetheine binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

458965

LYS5
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

2

0

High-throughput

0.761

High

458961

ECM1
Shuttling pre-60S factor ECM1

2

0

High-throughput

0.563

High

458949

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.536

High

458953

SIS1
Protein SIS1

2

2

High-throughput

0.521

High

458957

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

458959

RCK2
Serine/threonine-protein kinase RCK2

1

1

High-throughput

0.479

High

458960

ECM29
Proteasome component ECM29

1

2

High-throughput

0.479

High

458963

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

458948

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

458967

RBX1
RING-box protein HRT1

1

2

High-throughput

0.457

High

458947

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.445

High

458950

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

458951

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

458952

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.445

High

458955

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

458956

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

458962

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

458964

DPH4
Diphthamide biosynthesis protein 4

1

2

High-throughput

0.445

High

458954

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

458968

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

458958

FES1
Hsp70 nucleotide exchange factor FES1

1

0

High-throughput

0.269

Low

458969

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.269

Low

458966

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025