Protein: ECM1
Shuttling pre-60S factor ECM1 (Extracellular mutant protein 1) (Protein SIM1)

Gene: ECM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 119
UniProt ID: P39715

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0030687 - preribosome, large subunit precursor

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

813719

SXM1
Importin beta SMX1

4

0

Small-scale

0.658

High

734672

IMB3
Importin subunit beta-3

3

1

Small-scale

0.643

High

684733

RL5
Large ribosomal subunit protein uL18

3

0

Small-scale

0.606

High

813695

IMB4
Importin subunit beta-4

2

1

High-throughput

0.588

High

813710

NOG2
Nucleolar GTP-binding protein 2

2

1

Small-scale

0.584

High

427285

RLA0
Large ribosomal subunit protein uL10

2

1

High-throughput

0.571

High

358222

ADH1
Alcohol dehydrogenase 1

2

0

High-throughput

0.563

High

458961

LYS2
L-2-aminoadipate reductase

2

0

High-throughput

0.563

High

579421

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.563

High

813717

ARX1
Probable metalloprotease ARX1

2

0

Small-scale

0.559

High

544940

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

531747

RL4A
Large ribosomal subunit protein uL4A

2

0

High-throughput

0.547

High

433650

RL26A
Large ribosomal subunit protein uL24A

2

1

High-throughput

0.533

High

721949

XPO1
Exportin-1

1

0

High-throughput

0.513

High

509559

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

812218

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.493

High

433210

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.479

High

436418

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

689037

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

689218

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

750083

MRT4
Ribosome assembly factor MRT4

1

1

Small-scale

0.479

High

813702

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.479

High

813707

LSG1
Large subunit GTPase 1

1

1

High-throughput

0.479

High

813711

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.479

High

479263

CDC6
Cell division control protein 6

1

0

Small-scale

0.460

High

813693

ECM1
Shuttling pre-60S factor ECM1

1

0

Small-scale

0.460

High

813704

NU192
Nucleoporin NUP192

1

0

Small-scale

0.460

High

149774

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383310

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

410144

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

415018

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

432588

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

435975

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

441916

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

512449

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

569790

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

570021

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

628067

FKBP
FK506-binding protein 1

1

0

Small-scale

0.458

High

646411

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

679699

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

689467

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

707149

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734990

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

739372

ZUO1
Zuotin

1

0

Small-scale

0.458

High

745745

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

757878

UBX1
UBX domain-containing protein 1

1

0

Small-scale

0.458

High

778337

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

781195

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.458

High

790249

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

792521

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

797739

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

798500

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

1

0

High-throughput

0.458

High

802184

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

806127

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.458

High

808822

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

813694

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

813696

NSA2
Ribosome biogenesis protein NSA2

1

0

Small-scale

0.458

High

813700

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

813701

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

813703

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.458

High

813705

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.458

High

813706

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

813709

REXO1
RNA exonuclease 1

1

0

High-throughput

0.458

High

813712

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

813715

NOG1
Nucleolar GTP-binding protein 1

1

0

Small-scale

0.458

High

813716

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

813718

HMO1
High mobility group protein 1

1

0

High-throughput

0.458

High

813722

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

813723

RLP24
Ribosome biogenesis protein RLP24

1

0

Small-scale

0.458

High

813724

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.458

High

813726

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

813727

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

813728

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

813732

MEX67
mRNA export factor MEX67

1

0

High-throughput

0.458

High

741615

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

813697

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

383129

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.437

High

427701

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.437

High

433025

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.437

High

601048

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.437

High

712574

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.437

High

813698

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.437

High

813699

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.437

High

813708

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.437

High

813713

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.437

High

813714

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.437

High

813729

RL21B
Large ribosomal subunit protein eL21B

1

1

High-throughput

0.437

High

813730

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.437

High

394580

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

444521

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.426

High

450591

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

526743

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

592268

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

645420

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.426

High

676728

GBP2
Serine/arginine

1

0

High-throughput

0.426

High

752281

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

802081

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.426

High

813720

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.426

High

755102

GCN1
eIF-2-alpha kinase activator GCN1

2

0

High-throughput

0.307

High

154171

RL36B
Large ribosomal subunit protein eL36B

1

0

High-throughput

0.249

Low

383709

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

432845

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.249

Low

434023

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.249

Low

434376

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.249

Low

434574

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.249

Low

455072

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

504220

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

511425

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

511570

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.249

Low

513018

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

513688

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

515103

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

747373

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

753379

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

812308

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

813725

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.249

Low

813731

YPR08
Uncharacterized protein YPR108W-A

1

0

Small-scale

0.249

Low

813721

NCS1
Calcium-binding protein NCS-1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025