Interactor 1: IL12B (P29460)
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2)
Gene: IL12B
Interactor 2: IL23R (Q5VWK5)
Interleukin-23 receptor (IL-23 receptor) (IL-23R)
Gene: IL23R
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.60 | 0.536 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12023369 |
| Identification Methods | solid phase assay, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0002230 - positive regulation of defense response to virus by host GO:0002827 - positive regulation of T-helper 1 type immune response GO:0004896 - cytokine receptor activity GO:0007259 - cell surface receptor signaling pathway via JAK-STAT and 15 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025