Protein: LOX15
Polyunsaturated fatty acid lipoxygenase ALOX15 (12/15-lipoxygenase) (Arachidonate 12-lipoxygenase, leukocyte-type) (12-LOX) (EC 1.13.11.31) (Arachidonate 15-lipoxygenase) (15-LOX) (15-LOX-1) (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (Hepoxilin A3 synthase Alox15) (EC 1.13.11.-) (Linoleate 13S-lipoxygenase) (EC 1.13.11.12)

Gene: LOX15, ALOX15
Organism: Homo sapiens
Interactions: 12
UniProt ID: P16050

Gene Ontology (top 5):
GO:0001503 - ossification
GO:0002820 - negative regulation of adaptive immune response
GO:0004052 - arachidonate 12(S)-lipoxygenase activity
GO:0005506 - iron ion binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

590994

DD19B
ATP-dependent RNA helicase DDX19B

2

1

High-throughput

0.611

High

590993

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

590984

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

Small-scale

0.513

High

590985

STAT6
Signal transducer and activator of transcription 6

1

0

Small-scale

0.493

High

590991

SARAF
Store-operated calcium entry-associated regulatory factor

1

1

High-throughput

0.489

High

590986

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

467228

MDR1
ATP-dependent translocase ABCB1

1

0

High-throughput

0.458

High

590987

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

Small-scale

0.458

High

590990

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

0

Small-scale

0.458

High

590992

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

2

0

High-throughput

0.324

High

590988

SSBP2
Single-stranded DNA-binding protein 2

1

0

High-throughput

0.279

Low

590989

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025