Protein: NPD
NAD-dependent protein deacylase (EC 2.3.1.286) (Regulatory protein SIR2 homolog)

Gene: NPD, cobB
Organism: Escherichia coli K-12
Interactions: 22
UniProt ID: P75960

Gene Ontology (top 5):
GO:0003950 - NAD+ poly-ADP-ribosyltransferase activity
GO:0005737 - cytoplasm
GO:0006935 - chemotaxis
GO:0008270 - zinc ion binding
GO:0017136 - histone deacetylase activity, NAD-dependent

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1003730

NPD
NAD-dependent protein deacylase

1

13

High-throughput

0.698

High

501357

RS14
Small ribosomal subunit protein uS14

3

0

High-throughput

0.629

High

494197

RS4
Small ribosomal subunit protein uS4

2

0

High-throughput

0.545

High

494510

RS9
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

950981

RL2
Large ribosomal subunit protein uL2

1

2

High-throughput

0.536

High

491693

KPRS
Ribose-phosphate pyrophosphokinase

1

2

High-throughput

0.527

High

493443

RS13
Small ribosomal subunit protein uS13

1

0

High-throughput

0.513

High

501214

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.513

High

501262

RL21
Large ribosomal subunit protein bL21

1

0

High-throughput

0.513

High

811713

USPG
Universal stress protein UP12

1

0

High-throughput

0.513

High

477376

T1RK
Type I restriction enzyme EcoKI endonuclease subunit

1

4

High-throughput

0.489

High

578354

DNLJ
DNA ligase

1

2

High-throughput

0.479

High

493664

RS20
Small ribosomal subunit protein bS20

1

0

High-throughput

0.464

High

493996

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.464

High

496639

LDCI
Inducible lysine decarboxylase

1

0

High-throughput

0.464

High

489369

ISCS
Cysteine desulfurase IscS

1

3

High-throughput

0.442

High

1003705

SXY
Protein Sxy

2

0

High-throughput

0.343

High

1003732

YDGJ
Uncharacterized oxidoreductase YdgJ

2

0

High-throughput

0.318

High

1003731

VXIS
Prophage excisionase-like protein

1

0

High-throughput

0.279

Low

501114

SPOT
Bifunctional

1

0

High-throughput

0.249

Low

852140

KDSD
Arabinose 5-phosphate isomerase KdsD

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025