Protein: FXL22
F-box and leucine-rich protein 22

Gene: FXL22, FBXL22
Organism: Homo sapiens
Interactions: 12
UniProt ID: Q6P050

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0030018 - Z disc
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992215

SKP1
S-phase kinase-associated protein 1

4

1

Small-scale

0.911

High

1112551

CUL1
Cullin-1

1

0

Small-scale

0.656

High

773751

ACTN2
Alpha-actinin-2

1

1

Small-scale

0.586

High

1125349

FLNC
Filamin-C

1

3

Small-scale

0.573

High

557350

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.536

High

902851

BLK
Tyrosine-protein kinase Blk

1

1

High-throughput

0.536

High

922446

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

968639

NCS1
Neuronal calcium sensor 1

1

0

High-throughput

0.513

High

482621

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

0

High-throughput

0.279

Low

1051773

EF1A2
Elongation factor 1-alpha 2

1

0

High-throughput

0.279

Low

1240286

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

0

High-throughput

0.279

Low

1240287

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025