Protein: END8
Endonuclease 8 (DNA glycosylase/AP lyase Nei) (EC 3.2.2.-, EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) (Endonuclease VIII)

Gene: END8, nei
Organism: Escherichia coli K-12
Interactions: 14
UniProt ID: P50465

Gene Ontology (top 5):
GO:0000703 - oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0003684 - damaged DNA binding
GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0006284 - base-excision repair
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

496820

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

2

0

High-throughput

0.563

High

895858

RL4
Large ribosomal subunit protein uL4

2

1

High-throughput

0.537

High

497042

DLDH
Dihydrolipoyl dehydrogenase

1

0

High-throughput

0.513

High

489891

CH60
Chaperonin GroEL

3

0

High-throughput

0.347

High

492986

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.307

High

494176

RS4
Small ribosomal subunit protein uS4

2

0

High-throughput

0.307

High

499129

DBHB
DNA-binding protein HU-beta

2

0

High-throughput

0.307

High

501251

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.307

High

491675

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.279

Low

616952

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.279

Low

895860

PXPC
5-oxoprolinase subunit C

1

0

High-throughput

0.279

Low

501347

RS14
Small ribosomal subunit protein uS14

1

0

High-throughput

0.253

Low

895859

NFI
Endonuclease V

1

0

High-throughput

0.253

Low

490184

CH10
Co-chaperonin GroES

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025