Protein: SGPL
Sphingosine-1-phosphate lyase (S1PL) (SP-lyase) (ySPL) (EC 4.1.2.-) (EC 4.1.2.27) (Bestowed of sphingosine tolerance 1) (Sphingosine-1-phosphate aldolase)

Gene: SGPL, DPL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 34
UniProt ID: Q05567

Gene Ontology (top 5):
GO:0005777 - peroxisome
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006665 - sphingolipid metabolic process
GO:0008117 - sphinganine-1-phosphate aldolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1051630

SGPL
Sphingosine-1-phosphate lyase

3

17

Small-scale

0.867

High

671129

SIS1
Protein SIS1

2

2

High-throughput

0.571

High

680067

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

803687

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

1035095

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.457

High

527681

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

779578

LHS1
Heat shock protein 70 homolog LHS1

1

13

High-throughput

0.445

High

1051631

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

4

High-throughput

0.445

High

510821

HSP77
Import motor subunit, mitochondrial

1

12

High-throughput

0.437

High

580072

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.437

High

727312

HS104
Heat shock protein 104

1

3

High-throughput

0.437

High

795218

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

812659

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

865332

MTNB
Methylthioribulose-1-phosphate dehydratase

1

1

High-throughput

0.437

High

881441

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.437

High

922653

HST2
NAD-dependent protein deacetylase HST2

1

3

High-throughput

0.437

High

1045089

SXM1
Importin beta SMX1

1

2

High-throughput

0.437

High

632003

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

703849

LAC1
Ceramide synthase LAC1

1

0

High-throughput

0.426

High

525158

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.407

High

546280

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.407

High

739465

ZUO1
Zuotin

1

1

High-throughput

0.407

High

742397

HSP7F
Heat shock protein homolog SSE1

1

17

High-throughput

0.407

High

742948

HSP79
Heat shock protein homolog SSE2

1

17

High-throughput

0.407

High

752733

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

811398

CAJ1
Protein CAJ1

1

1

High-throughput

0.407

High

816409

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.407

High

823654

TCPE
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.407

High

558868

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

918996

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

925054

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

912446

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.232

Low

1051632

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025