Interactor 1: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2
Interactor 2: SREK1 (Q8WXA9)
Splicing regulatory glutamine/lysine-rich protein 1 (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) (Splicing regulatory protein 508) (SRrp508)
Gene: SREK1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.81 | 1.00 | 0.903 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 32707033, 23602568, unassigned3799 |
| Identification Methods | affinity chromatography technology, enzymatic study, pull down, anti tag coimmunoprecipitation, protein kinase assay |
| Interaction Type | physical association, direct interaction, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~RRM_1 |
| Common GO terms | GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0008380 - RNA splicing GO:0016607 - nuclear speck |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
