HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: WDR33 (Q9C0J8)
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa)
Gene: WDR33

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 1336
+	Hs
		1407533 TCPH_HUMAN (4-532): 0: 591: 34.08		TBL1Y_HUMAN (193-498): 5.03e-58: 211: 20.00
+	Hs
		1007231 TCPB_HUMAN (1-535): 0: 586: 100.00		TBL1Y_HUMAN (193-498): 5.03e-58: 211: 20.00
+	Hs
		1007186 TCPB_HUMAN (1-535): 0: 586: 100.00		FBXW7_HUMAN (229-428): 7.65e-42: 167: 21.89
+	Hs
		984251 TCPH_HUMAN (4-532): 0: 591: 34.08		GBB2_HUMAN (218-479): 4.72e-41: 156: 20.97
+	Hs
		984070 TCPB_HUMAN (1-535): 0: 586: 100.00		GBB2_HUMAN (218-479): 4.72e-41: 156: 20.97
+	Hs
		1007162 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1B_HUMAN (275-523): 2.05e-37: 149: 16.47
+	Hs
		209325 TCPH_HUMAN (4-532): 0: 591: 34.08		PRP4_HUMAN (275-480): 9.12e-29: 124: 16.13
+	Hs
		209247 TCPB_HUMAN (1-535): 0: 586: 100.00		PRP4_HUMAN (275-480): 9.12e-29: 124: 16.13
+	Hs
		1407594 TCPH_HUMAN (4-532): 0: 591: 34.08		NLE1_HUMAN (314-511): 2.54e-26: 116: 15.35
+	Hs
		1007305 TCPB_HUMAN (1-535): 0: 586: 100.00		NLE1_HUMAN (314-511): 2.54e-26: 116: 15.35
+	Hs
		1334162 TCPH_HUMAN (4-532): 0: 591: 34.08		POC1A_HUMAN (17-146): 1.2e-22: 104: 9.77
+	Hs
		1007146 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1A_HUMAN (17-146): 1.2e-22: 104: 9.77
+	Hs
		284939 TCPB_HUMAN (1-535): 0: 586: 100.00		TAF5L_HUMAN (121-319): 6.8e-14: 78.2: 23.00
+	Hs
		965190 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5_HUMAN (367-523): 7.86e-11: 67.3: 10.83
+	Hs
		1291941 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5B_HUMAN (367-543): 1.31e-10: 66.5: 10.73
+	Hs
		163653 TCPH_HUMAN (4-532): 0: 591: 34.08		GNB5_HUMAN (189-402): 1.05e-09: 64.3: 23.74
+	Hs
		964840 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5_HUMAN (367-523): 7.86e-11: 67.3: 10.83
+	Hs
		1007118 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5B_HUMAN (367-543): 1.31e-10: 66.5: 10.73
+	Hs
		163632 TCPB_HUMAN (1-535): 0: 586: 100.00		GNB5_HUMAN (189-402): 1.05e-09: 64.3: 23.74
+	Sc
		793919 TCPB_YEAST (9-532): 0: 566: 65.71		TAF5_YEAST (122-323): 2.13e-13: 77: 25.49