HitPredict

Interactor 1: H4 (P84040)
Histone H4
Gene: His4

Interactor 2: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	19001096
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 103 Dm			1 521
+	Hs
		980076 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Mm
		980640 H4_MOUSE (1-103): 1.72e-48: 151: 99.03		HDAC2_MOUSE (2-488): 0: 655: 76.18
+	Mm
		148671 H4_MOUSE (1-103): 1.72e-48: 151: 99.03		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		979614 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		188232 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	At
		947807 H4_ARATH (1-103): 4.24e-48: 150: 97.09		HDA6_ARATH (4-455): 0: 561: 59.44
+	Sc
		381960 H4_YEAST (18-103): 5.88e-41: 132: 90.70		RPD3_YEAST (4-419): 0: 573: 59.81
+	Sp
		149003 H4_SCHPO (18-103): 4.73e-42: 135: 89.54		PHD1_SCHPO (5-406): 0: 519: 52.84
+	Sc
		382228 H4_YEAST (18-103): 5.88e-41: 132: 90.70		HOS2_YEAST (8-409): 1.16e-168: 486: 50.48
+	Hs
		940901 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		HDAC4_HUMAN (5-405): 2.09e-133: 415: 22.86
+	Hs
		980270 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		HDAC8_HUMAN (30-369): 4.58e-139: 407: 42.82
+	Sc
		382267 H4_YEAST (18-103): 5.88e-41: 132: 90.70		HDA1_YEAST (6-327): 2.8e-116: 360: 26.42
+	Hs
		980479 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55