Interactor 1: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Interactor 2: MAML1 (Q92585)
Mastermind-like protein 1 (Mam-1)
Gene: MAML1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 11101851
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~MamL-1
Common GO terms GO:0003162 - atrioventricular node development
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007219 - Notch signaling pathway
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 2471
Hs

1 1016
+ Hs
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+ Dm
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+ Dm

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Last updated: 15 Jul 2024