HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: H2B3B (Q8N257)
Histone H2B type 3-B (H2B type 12) (H2B-clustered histone 26) (H2B.U histone 1)
Gene: H2BC26

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29044188
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 126
+	Hs
		659887 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1O_HUMAN (1-126): 3e-55: 170: 96.83
+	Hs
		998407 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B2F_HUMAN (1-126): 1.98e-55: 170: 95.24
+	Hs
		659889 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		H2B1O_HUMAN (1-126): 3e-55: 170: 96.83
+	Hs
		998643 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1H_HUMAN (1-126): 5.85e-55: 169: 96.03
+	Hs
		998737 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1M_HUMAN (1-126): 5.42e-55: 169: 92.86
+	Hs
		256827 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1K_HUMAN (1-126): 2.02e-54: 168: 94.44
+	Hs
		449702 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1J_HUMAN (1-126): 1.18e-54: 168: 95.24
+	Hs
		754792 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1B_HUMAN (1-126): 1.93e-54: 168: 96.03
+	Hs
		943344 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2BFS_HUMAN (1-126): 1.85e-54: 168: 92.86
+	Hs
		980685 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1C_HUMAN (1-126): 1.77e-54: 168: 95.24
+	Hs
		998371 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B2E_HUMAN (1-126): 9.48e-55: 168: 96.03
+	Hs
		256833 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		H2B1K_HUMAN (1-126): 2.02e-54: 168: 94.44
+	Hs
		449708 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		H2B1J_HUMAN (1-126): 1.18e-54: 168: 95.24
+	Mm
		533447 H31_MOUSE (1-136): 3.09e-60: 183: 96.32		H2B1M_MOUSE (1-126): 4.11e-54: 167: 95.24
+	Hs
		754799 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		H2B1B_HUMAN (1-126): 1.93e-54: 168: 96.03
+	Hs
		946747 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1D_HUMAN (1-126): 4.11e-54: 167: 95.24
+	Mm
		533449 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		H2B1M_MOUSE (1-126): 4.11e-54: 167: 95.24
+	Hs
		998738 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1L_HUMAN (1-126): 5.28e-53: 164: 95.24
+	Hs
		998535 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B3B_HUMAN (1-126): 1.04e-52: 163: 100.00
+	Hs
		998649 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		H2B1A_HUMAN (1-126): 3.86e-47: 149: 85.83