Interactor 1: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Interactor 2: APC4 (Q9UJX5)
Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)
Gene: ANAPC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 24464857, 25750436, 24151075, 25673878, 26986935, 23007648, 27097363, 27939943, 28404789, 32152539, 35271311, 21926987, 21336306, 18471975, 23160376, 23078409, 25043029, 25306918, 26811472, 27114510 and 5 others

more...

Identification Methods affinity chromatography technology, pull down, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4_WD40~ANAPC4_WD40, ANAPC4_WD40~WD40
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 499
Hs

1 808
+ Hs
+ At
+ At
+ At
+ At
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024