HitPredict

Interactor 1: BACH1 (P97302)
Transcription regulator protein BACH1 (BTB and CNC homolog 1)
Gene: BACH1

Interactor 2: MAFK (Q61827)
Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit)
Gene: MAFK

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.710

Property	Details
Experiments	19011633
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	bZIP_Maf~bZIP_Maf
Common GO terms	GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 739 Mm			1 156
+	Mm
		236425 BACH1_MOUSE (1-739): 0: 568: 100.00		MAFG_MOUSE (1-148): 2.78e-55: 172: 70.99
+	Hs
		166584 BACH1_HUMAN (1-739): 0: 537: 79.60		MAFF_HUMAN (1-148): 1.77e-65: 198: 66.89
+	Hs
		166474 BACH1_HUMAN (1-739): 0: 537: 79.60		MAFK_HUMAN (1-156): 4.52e-63: 192: 98.08
+	Hs
		166469 BACH1_HUMAN (1-739): 0: 537: 79.60		MAFG_HUMAN (1-148): 7.03e-55: 171: 71.61
+	Hs
		166585 BACH1_HUMAN (1-739): 0: 537: 79.60		MAFB_HUMAN (18-128): 8.57e-48: 158: 53.91
+	Hs
		166479 BACH1_HUMAN (1-739): 0: 537: 79.60		MAF_HUMAN (22-114): 1.03e-45: 154: 58.07
+	Mm
		1021109 BACH2_MOUSE (2-739): 1.57e-124: 393: 29.24		MAFK_MOUSE (1-156): 9.44e-64: 194: 100.00
+	Hs
		1419362 BACH2_HUMAN (1-739): 1.29e-109: 354: 28.45		MAFF_HUMAN (1-148): 1.77e-65: 198: 66.89
+	Hs
		253415 BACH2_HUMAN (1-739): 1.29e-109: 354: 28.45		MAFK_HUMAN (1-156): 4.52e-63: 192: 98.08
+	Hs
		193348 BACH2_HUMAN (1-739): 1.29e-109: 354: 28.45		MAFG_HUMAN (1-148): 7.03e-55: 171: 71.61
+	Hs
		1419365 BACH2_HUMAN (1-739): 1.29e-109: 354: 28.45		MAFB_HUMAN (18-128): 8.57e-48: 158: 53.91
+	Hs
		1156716 NF2L2_HUMAN (406-660): 1.62e-67: 235: 26.20		MAFF_HUMAN (1-148): 1.77e-65: 198: 66.89
+	Hs
		253409 NF2L2_HUMAN (406-660): 1.62e-67: 235: 26.20		MAFK_HUMAN (1-156): 4.52e-63: 192: 98.08
+	Hs
		1461848 NF2L3_HUMAN (489-666): 5.14e-64: 228: 30.11		MAFF_HUMAN (1-148): 1.77e-65: 198: 66.89
+	Hs
		253421 NF2L3_HUMAN (489-666): 5.14e-64: 228: 30.11		MAFK_HUMAN (1-156): 4.52e-63: 192: 98.08
+	Rn
		236947 NF2L2_RAT (159-660): 1.19e-60: 216: 16.92		Q6IRI7_RAT (1-156): 3.92e-63: 192: 99.36
+	Hs
		193341 NF2L2_HUMAN (406-660): 1.62e-67: 235: 26.20		MAFG_HUMAN (1-148): 7.03e-55: 171: 71.61
+	Hs
		193357 NF2L3_HUMAN (489-666): 5.14e-64: 228: 30.11		MAFG_HUMAN (1-148): 7.03e-55: 171: 71.61
+	Hs
		282186 NF2L2_HUMAN (406-660): 1.62e-67: 235: 26.20		MAF_HUMAN (22-114): 1.03e-45: 154: 58.07
+	Mm
		236427 NF2L2_MOUSE (147-660): 6.36e-60: 214: 18.50		MAFG_MOUSE (1-148): 2.78e-55: 172: 70.99