HitPredict

Interactor 1: MAFG (O54790)
Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G)
Gene: MAFG

Interactor 2: BACH1 (P97302)
Transcription regulator protein BACH1 (BTB and CNC homolog 1)
Gene: BACH1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	19011633
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	bZIP_Maf~bZIP_Maf
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003677 - DNA binding GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 162 Mm			1 739
+	Hs
		166469 MAFG_HUMAN (1-162): 1.8e-69: 208: 98.77		BACH1_HUMAN (1-739): 0: 537: 79.60
+	Mm
		1021102 MAFK_MOUSE (1-157): 3.77e-53: 167: 73.25		BACH1_MOUSE (1-739): 0: 568: 100.00
+	Hs
		166584 MAFF_HUMAN (1-156): 3.52e-54: 170: 64.10		BACH1_HUMAN (1-739): 0: 537: 79.60
+	Hs
		166474 MAFK_HUMAN (1-156): 1.24e-52: 166: 73.72		BACH1_HUMAN (1-739): 0: 537: 79.60
+	Hs
		193348 MAFG_HUMAN (1-162): 1.8e-69: 208: 98.77		BACH2_HUMAN (1-739): 1.29e-109: 354: 28.45
+	Mm
		1021109 MAFK_MOUSE (1-157): 3.77e-53: 167: 73.25		BACH2_MOUSE (2-739): 1.57e-124: 393: 29.24
+	Hs
		1419362 MAFF_HUMAN (1-156): 3.52e-54: 170: 64.10		BACH2_HUMAN (1-739): 1.29e-109: 354: 28.45
+	Hs
		193341 MAFG_HUMAN (1-162): 1.8e-69: 208: 98.77		NF2L2_HUMAN (406-660): 1.62e-67: 235: 26.20
+	Hs
		193357 MAFG_HUMAN (1-162): 1.8e-69: 208: 98.77		NF2L3_HUMAN (489-666): 5.14e-64: 228: 30.11
+	Mm
		236427 MAFG_MOUSE (1-162): 5.77e-70: 210: 100.00		NF2L2_MOUSE (147-660): 6.36e-60: 214: 18.50
+	Hs
		1156716 MAFF_HUMAN (1-156): 3.52e-54: 170: 64.10		NF2L2_HUMAN (406-660): 1.62e-67: 235: 26.20
+	Hs
		1461848 MAFF_HUMAN (1-156): 3.52e-54: 170: 64.10		NF2L3_HUMAN (489-666): 5.14e-64: 228: 30.11
+	Rn
		236947 Q6IRI7_RAT (1-157): 8.02e-53: 166: 72.61		NF2L2_RAT (159-660): 1.19e-60: 216: 16.92
+	Mm
		1221494 MAFK_MOUSE (1-157): 3.77e-53: 167: 73.25		NF2L2_MOUSE (147-660): 6.36e-60: 214: 18.50
+	Hs
		193340 MAFG_HUMAN (1-162): 1.8e-69: 208: 98.77		NF2L1_HUMAN (527-627): 2.06e-18: 92: 47.53
+	Mm
		236426 MAFG_MOUSE (1-162): 5.77e-70: 210: 100.00		NFE2_MOUSE (527-627): 4.58e-17: 85.5: 45.55
+	Hs
		193342 MAFG_HUMAN (1-162): 1.8e-69: 208: 98.77		NFE2_HUMAN (527-627): 5.92e-17: 85.5: 45.55
+	Hs
		193320 MAFG_HUMAN (1-162): 1.8e-69: 208: 98.77		ZBT24_HUMAN (2-125): 8.7e-12: 70.5: 33.07
+	Hs
		1126872 MAFF_HUMAN (1-156): 3.52e-54: 170: 64.10		NF2L1_HUMAN (527-627): 2.06e-18: 92: 47.53
+	Mm
		1059003 MAFK_MOUSE (1-157): 3.77e-53: 167: 73.25		NFE2_MOUSE (527-627): 4.58e-17: 85.5: 45.55