HitPredict

Interactor 1: SOCS1 (O35716)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1)
Gene: SOCS1

Interactor 2: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21731497
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 212 Mm			1 424
+	Mm
		619089 DAPP1_MOUSE (52-201): 7.61e-38: 134: 20.63		IRF8_MOUSE (1-424): 0: 586: 100.00
+	Hs
		181861 SOCS1_HUMAN (1-212): 2.59e-45: 151: 94.81		IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72
+	Hs
		181882 SOCS1_HUMAN (1-212): 2.59e-45: 151: 94.81		IRF7_HUMAN (12-383): 4.85e-111: 337: 21.46
+	Hs
		147439 SOCS3_HUMAN (40-208): 2.32e-42: 144: 27.27		IRF7_HUMAN (12-383): 4.85e-111: 337: 21.46
+	Hs
		181780 SOCS1_HUMAN (1-212): 2.59e-45: 151: 94.81		IRF1_HUMAN (9-266): 9.31e-86: 266: 27.27
+	Mm
		193340 SOCS1_MOUSE (1-212): 3.72e-50: 163: 100.00		IRF1_MOUSE (9-263): 5.48e-75: 238: 25.57
+	Hs
		181784 SOCS1_HUMAN (1-212): 2.59e-45: 151: 94.81		IRF2_HUMAN (9-167): 5.93e-59: 197: 37.50