HitPredict

Interactor 1: THIOM (P97493)
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)
Gene: Txn2

Interactor 2: THIOM (P97493)
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)
Gene: Txn2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29222160
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Thioredoxin~Thioredoxin
Common GO terms	GO:0005730 - nucleolus GO:0005739 - mitochondrion GO:0015035 - protein-disulfide reductase activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 166 Mm			1 166
+	Hs
		452382 THIOM_HUMAN (1-166): 3.09e-55: 173: 88.55		PDIA1_HUMAN (52-166): 9.36e-35: 128: 27.50
+	Ss
		910344 THIO_SYNY3 (59-165): 4.91e-39: 130: 31.78		THIO_SYNY3 (59-165): 4.91e-39: 130: 31.78
+	Hs
		452129 PDIA1_HUMAN (52-166): 9.36e-35: 128: 27.50		PDIA1_HUMAN (52-166): 9.36e-35: 128: 27.50
+	Sc
		673323 TRX3_YEAST (47-164): 2.4e-37: 126: 29.66		TRX3_YEAST (47-164): 2.4e-37: 126: 29.66
+	Sc
		652850 TRX2_YEAST (61-154): 2.22e-36: 123: 31.92		TRX2_YEAST (61-154): 2.22e-36: 123: 31.92
+	Sc
		646584 TRX2_YEAST (61-154): 2.22e-36: 123: 31.92		TRX1_YEAST (61-154): 6.49e-36: 122: 37.23
+	Sp
		154276 TRX1_SCHPO (61-162): 5.64e-36: 122: 35.29		TRX1_SCHPO (61-162): 5.64e-36: 122: 35.29
+	Hs
		452145 PDIA1_HUMAN (52-166): 9.36e-35: 128: 27.50		PDIA4_HUMAN (60-165): 1.13e-28: 112: 27.52
+	Mm
		479089 PDIA1_MOUSE (57-166): 1.74e-31: 119: 30.44		PDIA1_MOUSE (57-166): 1.74e-31: 119: 30.44
+	Hs
		717481 PDIA6_HUMAN (62-165): 1.24e-32: 122: 23.81		PDIA3_HUMAN (49-163): 3.44e-30: 115: 23.53
+	Hs
		452245 PDIA1_HUMAN (52-166): 9.36e-35: 128: 27.50		PDIA2_HUMAN (62-166): 1.51e-27: 108: 26.36
+	Ss
		910421 THIO1_SYNY3 (65-151): 2.31e-34: 118: 31.03		THIO1_SYNY3 (65-151): 2.31e-34: 118: 31.03
+	Hs
		566679 PDIA6_HUMAN (62-165): 1.24e-32: 122: 23.81		PDIA4_HUMAN (60-165): 1.13e-28: 112: 27.52
+	Zm
		1204262 Q5EUD7_MAIZE (58-162): 3.78e-31: 116: 30.56		Q5EUD7_MAIZE (58-162): 3.78e-31: 116: 30.56
+	Dm
		1465013 THIO2_DROME (61-162): 5.97e-37: 124: 37.86		PDIA6_DROME (65-153): 2.14e-27: 107: 25.56
+	Hs
		717371 PDIA3_HUMAN (49-163): 3.44e-30: 115: 23.53		PDIA3_HUMAN (49-163): 3.44e-30: 115: 23.53
+	Dm
		1465092 THIO2_DROME (61-162): 5.97e-37: 124: 37.86		Q9W022_DROME (62-161): 5.33e-29: 105: 49.00
+	Hs
		566571 PDIA3_HUMAN (49-163): 3.44e-30: 115: 23.53		PDIA4_HUMAN (60-165): 1.13e-28: 112: 27.52